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Table 2 The anti-cancer properties of some typical GLP compounds

From: A review of anti-tumour effects of Ganoderma lucidum in gastrointestinal cancer

GLP

Cancer

Anti-cancer mechanisms

Refs.

Inhibiting proliferation

Inducing apoptosis

Inhibiting metastasis

Regulating autophagy

FYGL

Pancreatic cancer

−

 + 

−

 + 

[57]

WSG

Tongue cancer

−

 + 

−

−

[58]

WSG

Lung cancer

−

−

 + 

−

[13]

SeGLP-2B-1

Breast cancer

 + 

 + 

−

−

[59]

(1,3)-β-D-Glucan derivative

Lymphoma

 + 

−

−

−

[60]

LZP-F3

Leukemia

−

 + 

−

−

[61]

LZP-F3

Urothelial carcinoma

−

 + 

−

−

[62]

SCGLP1

Osteosarcoma

 + 

 + 

−

−

[63]

GL-IV-I

Sarcoma

 + 

 + 

−

−

[64]

Ganoderan B

NSCLC

−

 + 

 + 

−

[65]

Ganopoly

Cancer

 + 

 + 

−

−

[66]

SeGLP-2B-1

Cancer

 + 

−

−

−

[67]

GLP-1–1

Cancer

 + 

−

−

−

[68]

β-glucan

Colon cancer

 + 

−

−

−

[69]

  1. FYGL Fudan-Yueyang-G. lucidum; LZP-F3 Ling-zhi polysaccharide fraction 3; SCGLP1 Sulfated polysaccharide; NSCLC Non-small cell lung cancer; GL-PP G. lucidum peptide
  2.  + : have the properties; -: lack of this properties