Fig. 5
From: Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia
Effects of YXT and its components on COX-1 and COX-2 activities. COX-1 and COX-2 activity assay kits were used to monitor the COX enzymatic activities. Ethanol extracts of YXT or its herbal components (100 µg/mL) were mixed with respective COX enzymes (COX-1 or COX-2), COX assay buffer, arachidonic acid in NaOH, and a fluorescence probe. Fluorometric reading of enzyme control (Con) was defined as 100% COX activity. COX-1 specific inhibitor SC560 (SC) and COX-2 specific inhibitor celecoxib (Cel) served as controls. *P < 0.05 (ANOVA); n = 7