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Fig. 2 | Chinese Medicine

Fig. 2

From: A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

Fig. 2

TCM targeting ferroptosis against cancer. ACP the root of Actinidia chinensis Planch, LBP Lycium barbarum polysaccharide, FZKA Fuzhengkang'ai decoction, YQHY Yiqi Huayu decoction. Oleanolic acid, ruscogenin and other compounds induce ferroptosis by affecting iron metabolism. Nobiletin, tagitinin C and other compounds act on the p62-Keap1-Nrf2pathway to lead to ferroptosis. Scutellaria barbata, dihydroisotanshinone I and other Chinese medicine result in ferroptosis by functioning in GPX4-GSH axis. Tanshinone IIA, gambogic acid and curcumin induce ferroptosis by modulating p53. Atractylodin and others cause lipidperoxidation by activating ACSL4

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Chinese Medicine

ISSN: 1749-8546

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