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Fig. 1 | Chinese Medicine

Fig. 1

From: Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway

Fig. 1

JGSQ improves retinal lesions in db/db mice with DR. A The relative blood glucose value of db/db and db/m mice. B The body weight of db/db and db/m mice, weighed once every 2 weeks. C Images of H&E staining of retina from mice (magnification × 20). The image was captured by CaseViewer. D The thickness of outer nuclear layer (ONL) were measured by Adobe Illustrate. E The number of ganglion cells were calculated by Image J. F PAS staining of retinal vascular network patches (magnification × 40) were used to identify the abnormal lesions of retinal blood vessels. Mock VS Model. nsP > 0.05, #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001. JGSQ-treated VS Model, Positive VS Model. nsP > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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