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Fig. 3 | Chinese Medicine

Fig. 3

From: Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway

Fig. 3

Network pharmacology analysis of JGSQ in the treatment of DR. A A venn diagram between targets for JGSQ and DR targets, which may represent potential targets for the treatment of DR with JGSQ; B JGSQ-Ingredient-DR Intersection Target Network, core nodes of the network were identified as targets with high Betweenness Centrality, Closeness Centrality, and Degree greater than the median. C PPI network of JGSQ in treating DR, the size and color of nodes reflect the size of the Degree, with larger nodes indicating higher Degree values. The thickness of edges is used to reflect the size of the Combine score, with thicker edges indicating higher Combine scores. This graph is used to select core targets for constructing a PPI network; D GO enrichment analysis; E KEGG enrichment analysis

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