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Fig. 4 | Chinese Medicine

Fig. 4

From: Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway

Fig. 4

Molecular docking. Diosgenin is the main active compound that can bind with key targets. A Diosgenin binds AKT1; B Diosgenin binds GAPDH; C Diosgenin binds IL6; D Diosgenin binds TNF; E Diosgenin binds TP53. F, G The expression levels of cleaved caspase 3 and caspase 9 in retinal tissue using ELISA. H, I Western blot detected the expression of cleaved PARP in db/db mice retina tissue

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