Fig. 2

Effects of samples on body weight and glucose metabolism in diabetic mice. a Body weight of mice during the treatment. b Fasting blood glucose (FBG) of mice in each group at the end of drug treatment. c The OGTT was measured on day 36 after drug administration. d The AUC of glucose for the OGTT test. e The ITT was measured on day 39 after drug administration. f The AUC of glucose for the ITT test. g The fasting serum insulin level of mice. h The homeostasis model assessment-insulin resistance (HOMA-IR) index of mice. N: normal control group (db/m mice); M: model group (db/db mice); CR TD, CR DG, SC TD, SC DG, and P: db/db mice treated with CR TD, CR DG, SC TD, SC DG, and metformin. Data were expressed as the mean ± SD (n = 6 mice per group). ^###p < 0.001 versus N group; *p < 0.05, **p < 0.01, ***p < 0.001 versus M group; ⁺⁺⁺p < 0.001 versus SC TD group. Data were analyzed by one-way-ANOVA.