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Table 2 Cytotoxicity against A549 and H1975 cells of compounds 1 − 7, and 10 − 13

From: Prenylated chromones and flavonoids isolated from the roots of Flemingia macrophylla and their anti-lung cancer activity

Compd.

24h IC50 (μmol·L-1)

A549 cells

H1975 cells

1a

79.89 ± 3.66

21.42 ± 1.22***

1b

49.27 ± 1.81***

 < 5***

2

36.59 ± 1.01***

20.25 ± 0.65***

3

43.49 ± 3.62***

28.46 ± 0.53***

4

 > 100

42.77 ± 1.60***

5

4.50 ± 0.87***

 < 5***

6

19.83 ± 0.78***

 < 5***

7a

19.25 ± 0.13***

 < 5***

7b

19.07 ± 0.07***

 < 5***

10

 > 100

 > 100

11

 > 100

 > 100

12

 > 100

46.32 ± 0.85***

13

 > 100

 > 100

Icaritinb

74.24 ± 1.46

15.16 ± 0.18

  1. aEach data is shown as the mean ± SD calculated from three replicate determinations
  2. bPositive control
  3. ***P < 0.001 versus the blank control group