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Table 3 The EC50 values of PVE30 at different virus infectious cycles evaluated by the plaque reduction assay (Unit: μg/mL)

From: Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation

 

HSV-1/KOS

HSV-2/G

Pre-infection

 > 100

 > 100

Attachment

4.53 ± 0.21***

4.61 ± 0.40***

Penetration

27.86 ± 2.58*

22.77 ± 2.50

Post-infection

33.36 ± 0.77

26.61 ± 0.86

  1. Antiviral effects were evaluated by a plaque reduction assay to determine the 50% effective concentration (EC50)
  2. Values represent the mean ± S.D. from three independent experiments with each treatment performed in duplicate
  3. ***P < 0.001, *P < 0.05, vs. post-infection group
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Chinese Medicine

ISSN: 1749-8546

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