Fig. 3

The neuroprotective effect of compounds on MCAO in mice. A Timeline for determining the optimal post-stroke dosage in mice, with compounds administered daily via intragastric gavage at doses of 5, 10, and 20 mg/kg/day (or saline). B Treatment with compounds led to a decrease in infarct volume. Shown are representative brain slices with triphenyltetrazolium chloride (TTC)-stained infarcts from each group at 3 days post-MCAO. C Quantification of infarct volume at 3 days after MCAO. n = 5 per group. ***P < 0.001, vs. vehicle group