Fig. 4

Combination of Atr I, Atr III, and Pae applied after MCAO reduces mortality and neurological dysfunction. A Experimental design schematic. B Representative laser speckle imaging. C Histogram of cerebral blood flow. P < 0.001, N = 10 per group. The result showed no difference in the rate of decline in cerebral blood flow between the two groups. D Survival curve up to 14 days after MCAO. (E, F) Neurological behavior tests were performed with E Beam walking test and F Rotarod test. n = 5 mice for MCAO group, n = 8 for MCAO + Compounds group. *p < 0.05 vs. MCAO control group