Fig. 8

S.C treatment inhibits cancer progression in DU145 xenograft model. DU145 cells were subcutaneously injected into the flank of NCG nude mice. 10 days after inoculation, the mice were treated with S.C (2.5, 5.0 mg/kg body weight) via the intraperitoneal (i.p) route every 2 days. a 2 weeks after injection, tumor tissues were excised and photographed. The excised tumor weight b and volume c were calculated. d Body weight was measured every 2 days after administration of S.C. e Tumor volume was calculated every 2 days after administration of S.C. f Representative images of H&E and immunohistochemical staining for Ki67 and HMOX1 g protein levels of GPX4, SLC7A11, caspase3, HMOX1, USP47 and BACH1 measured by western blot