Fig. 2
Evaluation on the bone formation and bone defect repair of rats in different groups based on Micro-CT analysis. A Representative 3D images of rat tibia with both exterior and interior general view at the 21st day post-surgery. B–L Results of bone morphometric parameters analysis (ANOVA, followed by Bonferron’s post hoc test; bars show mean ± SD; #P < 0.05, ##P < 0.01 and ###P < 0.001 indicate the statistical significance compared to the normal control group, respectively; *P < 0.05, **P < 0.01 and ***P < 0.001 indicate the statistical significance compared to the model group, respectively). B Bone mineral density (BMD; g/cm3). C Bone volume/tissue volume ratio (BV/TV; %). D Structural model index (SMI). E Cortical bone thickness (Ct.Th; mm). F Cortical bone cross-sectional area ratio (Ct.Ar/T.Ar; %). G Connectivity density (Conn.D; mm−3). H Total porosity (Po(tot); %). I Trabecular number (Tb.N; mm−1). J Trabecular thickness (Tb.Th; mm). K Trabecular separation (Tb.Sp; mm). L Trabecular factor (Tb.Pf; mm−1)