Fig. 9
From: Quercetin inhibits caspase-1-dependent macrophage pyroptosis in experimental folic acid nephropathy
Quercetin inhibits CASP-1 expression and related pyroptosis in RAW264.7 cells. A Cytotoxic assessment of quercetin in RAW264.7 cells; B cytotoxic assessment of folic acid in RAW264.7 cells; C, D immunoblots and quantitative histograms showing the results of Western blot analysis for the expression of protein related to pyroptosis; E representative microscopy images of cells stained for F4/80+ (green), CASP-1 (red) and nuclei (blue) to detect expression of CASP-1 (Scale bars: 50 μm); F quantitative analysis of CASP-1 positive area in cells. Data represent mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001