Fig. 2
From: The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin
Liquiritigenin mitigates bleomycin-induced pulmonary oxidative stress in Mice. A DHE staining reflects lung ROS levels. Scale bars represent 100 μm. B–D Biochemical quantification of MDA and GSH levels, as well as SOD activity. E, F mRNA levels of HO-1 and NQO-1 analyzed by qPCR. G–J Protein expression levels of CAT, HO-1, and NQO-1 determined by Western blotting. Data are presented as means ± standard deviation, and all experiments were independently repeated at least three times. (*P < 0.05, **P < 0.01, ***P < 0.001)