Fig. 5

A The top 15 signaling pathways of KEGG pathway enrichment analysis for the KCSG in treatment of POI. B The relationship between the core targets with the active ingredients of KCSG and pathways, and the distribution of the KCSG in the POI network. The orange octagons stand for the composition of KCSG's herb, and the pentagon stand for the active ingredient in KCSG. The blue diamond represents the related pathways, and the ellipse nodes represent target genes. The size of nodes is in proportion to their degree