Fig. 2

PLD improves cell damage and inhibited pyroptosis-related inflammatory factors. a Cell survival rate of HNEpCs after treatment with different concentrations of PLD without LPS/ATP co-stimulation. b The half inhibition rate of PLD on HNEpCs. c, d Cell survival rate and LDH release of HNEpCs after treatment with different concentrations of PLD and LPS/ATP co-stimulation. (n = 5). e, f Expression levels of IL-18 and IL-1β in cell supernatant (n = 5). g–i WB images and statistical results of IL-18 and IL-1β (n = 3) (compared with Control group: *P < 0.05, **P < 0.01; compared with Model group: #P < 0.05, ##P < 0.01; compared with PLD 2.5 μM group: ☆P < 0.05)