Fig. 9From: Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitisPLD improves mitochondrial damage by activating the Nrf2/HO-1 antioxidant signaling pathway, reducing ROS production, and inhibiting the activation of NLRP3 inflammasome, thereby inhibiting pyroptosis and the inflammatory damage in HNEpCs of patients with CRSBack to article page