Fig. 5

Levels of CD28 (A), CTLA-4 (B), B7-1 (C), B7-2 (D), α-MSH (E), TrkB (F), 5-HT (G), BDNF (H) in serum of immunosuppressed rats (n = 8 per each group). Data are expressed as means ± SD, One-way ANOVA tests with LSD-t post-hoc tests executed. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 vs NG; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs CTX; ^%%p < 0.01, ^%%%p < 0.001 vs HPM. α-MSH: α-Melanocyte-stimulating hormone; TrkB: Tropomyosin receptor kinase B; 5-HT: 5-hydroxytryptamine; BDNF: Brain-derived neurotrophic factor; SD: standard deviation; ANOVA: analysis of variance; LSD-t: Least Significant Difference-t, NG: normal group; CTX: cyclophosphamide; HPM: Herb-partitioned moxibustion; aCD28: anti-CD28; aCTLA-4: anti-CTLA-4; LEV: Levamisole