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Fig. 3 | Chinese Medicine

Fig. 3

From: SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation

Fig. 3

SKP reduced ferroptosis of kidney tissues in DKD mice. A, B The levels of MDA (Malonaldehyde) and GSH(Glutathione) in kidney tissues of mice. C The mRNA levels of GPX4 in the kidneys of each group. D The quantitative analysis for immunohistochemical staining assays of GPX4. E Immunohistochemical staining assays of GPX4 in kidney tissues. (400 × magnification, bar = 100 µm). F, G Western blot for GPX4 in kidney tissues of each group and the quantitative analysis for Western blotting results of GPX4. H The levels of Iron Content in kidney tissues. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. control group. #P < 0.05, ##P < 0.01, and ###P < 0.001 vs. DKD group, ns no significance

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Chinese Medicine

ISSN: 1749-8546

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