Optimized New Shengmai Powder modulation of cAMP/Rap1A signaling pathway attenuates myocardial fibrosis in heart failure

Table 1 Screening conditions of ONSMP active ingredients

Filter conditions	Category	Class
Water Solubility	Log S (ESOL)	Soluble or moderately soluble or very soluble
	Log S (Ali)
	Log S (SILICOS-IT)
Pharmacokinetics	GI absorption	High
Druglikeness	Lipinski	Yes; 0 violation
	Ghose	Yes
	Veber	Yes
	Egan	Yes
	Muegge	Yes

ISSN: 1749-8546