Fig. 3
The Bufei Yishen formula increases the expression of the epithelial junction in COPD rats. BYF (11.6 g/kg) and doxophylline (Doxo: 36 mg/kg) were administered to COPD rats for 9 to 16 weeks. A The western bloting analysis of ZO-1, occludin, E-cadherin, p-ERK/1/2, and p-EGFR in the pulmonary tissue of COPD rats. B–F The quantitative analysis of the protein levels. Data are expressed as the mean ± SEM (n = 6), *P < 0.05, **P < 0.01, versus the control group; #P < 0.05, ##P < 0.01, versus the model group