Fig. 7

The active compounds of BYF prevent barrier dysfunction and activate SIRT1/AMPK/FoxO3-mediated autophagy in BEAS-2B cells exposed to CSE. A–J The expression of ZO-1, occludin, E-cadherin, LC3B, SIRT1, AMPK, p-AMPK, FOXO3a and p-FOXO3a in BEAS-2B cells treated with nobiletin (3, 10 μM), and the gray values were expressed as the target band /GAPDH. Data are expressed as the mean ± SEM (n = 3), *P < 0.05, **P < 0.01, versus the control group; ^#P < 0.05, ^##P < 0.01, versus the model group