Fig. 9From: LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signalingProposed mechanisms of ELG in protecting acute binge alcohol-induced fatty liver. The main effect of ELG in protecting against acute alcohol-induced fatty liver may through activation of AMPK in hepatocytes, thus inhibiting NLRP3/Caspase1/Il-1β signaling. Consequently, ELG inhibits inflammation and oxidative stress injury in hepatocytes and promots hepatic fatty acid oxidationBack to article page