Fig. 8

TSG inhibited the expression level of TNF-α and IL23. TSG and ginsenoside Rd in SBM were detected. A Chromatography profile of full scan UPLC/Q-TOF–MS/MS analysis for SBM sample in negative ion mode. B–C MS spectrum of the identified components in SBM from LC–MS dataset including TSG (B) and ginsenoside Rd. D Relative mRNA expression level analysis of TNF-α and IL23. GAPDH was used for standardization. HaCaT cells were stimulated with/without 50 ng/mL TNF-α and 5 μM TSG or 25, 50, 100 ng/mL SBM for 24 h. *P < 0.05, **P < 0.01 vs. vehicle group by one-way ANOVA with Tukey's multiple comparisons