Fig. 6

The anti-apoptotic, antioxidant and anti-inflammatory effects of Ta-IIA, As-IV and Co were weakened by diabZI. A Representative images of apoptotic cardiomyocytes. The apoptotic cells were detected by TUNEL (green), and the nuclei were detected by DAPI (blue). Scale bar = 50 μm. B The quantitative analysis of Tunel⁺ cells of (A). C Representative blots of the apoptosis-related proteins in myocardial tissue, as well as quantitative analysis of Bax, Bcl2, and Cleaved Caspase3. D Myocardial MDA content, GSH activity, SOD activity. E. The mRNA quantification of cytokines IL-6, IL-1β, TNFα, iNOS in cardiomyocardial tissues. Data are presented as mean ± SEM. (n = 6 in each group). *p < 0.05, **p < 0.01, ***p < 0.001