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Fig. 2 | Chinese Medicine

Fig. 2

From: Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)

Fig. 2

CAC extract prevented arthritis progression in CIA rats. A, B The hind paw volume (A) and arthritis index (AI) score (B) of hind paws in rats from: CON group (n = 6), CIA group (n = 6), CAC group (100 mg/kg/day, n = 6), MTX group (1 mg/kg/3 days, n = 6). C H&E staining of each group (scale bars: 50 μm). D–E IHC analysis of the expression of TNF-α (D) and IL-6 (E) in each group (scale bars: 25 μm). *P < 0.05 vs. CIA group; **P < 0.01 vs. CIA group; ***P < 0.001 vs. CIA group; ## P < 0.01 vs. control group; ### P < 0.001 vs. control group

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