Fig. 9

Illustration of the modulatory effects of GBP on the attenuation of drunkenness and ALD in mice. A schematic outlines the administration of GBP in mice and its subsequent inhibition of drunkenness and ALD symptoms (top left). A visual summary of the diversity of the gut microbiota within the intestinal lumen following GBP treatment (top right). A chart highlights the metabolic pathways altered after GBP treatment, notably glycerophospholipid metabolism, as suggested by the significant red marker (bottom left). The network diagram visualizes the complex interactions between bioactive agents, their molecular targets, and drunkenness or ALD genes. Nodes represent active agents that could play a role in modulating the impacts of alcohol (bottom right)