Fig. 3From: Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanomaPFKFB3 mediates CPT inhibition of glycolysis of melanoma. A The activity of three key kinases of aerobic glycolysis was measured in B16F10 cells treated with CPT. B The glycolysis related proteins in melanoma cells were detected by western blot. C The level of glycolysis related proteins mRNA in melanoma cells was measured. D The expression of PFKFB3 was detected by fluorescence assay. Compared with the control, * P < 0.05, ** P < 0.01, *** P < 0.001Back to article page