Table 3 The Application of Chinmedomics in Discovering Active Ingredients of TCM

Suan Zao Ren

Decoction

(SZRD)

Semen ziziphi spinosae, Rhizoma chuanxiong, Poria, Rhizoma anemarrhenae, Radixglycyrrhizae

Insomnia

Jatrorrhizine, Berberine, Obaculactone, Obacunone, Menisperine, p-hydroxybenzyl-6, Magnoflorine. Jujuboside A and Jujuboside B may be the pharmacodynamic material basis of SZRD in the treatment of insomnia

[84]

Sheng Mai San

(SMS)

Panax ginseng, Ophiopogon japonicus, Schisandrae Chinensis Fructus

Alzheimer’s disease (AD)

Schisandrin, Isoschisandrin, Angeloylgomisin Q, Gomisin D, Angeloylgomisin H, Gomisin M2, Ginsenoside F1, 20(R)-ginsenoside Rg3

[85]

Kai Xin San

(KXS)

Acorus tatarinowii Schott, Polygala tenuifolia Willd., Panax ginseng C. A. Mey., Poria cocos(Schw.Wolf)

Alzheimer’s disease (AD)

Ginsenoside Rf, Ginsenoside F1, 20-O-glucopyranosyl ginsenoside Rf, Dehydropachymic acid and E-3, 4, 5-trimethoxycinnamic acid

[86]

ZhiziBaipi Decoction (ZBD)

Gardenia jasminoides Ellis, Phellodendron amurense Rupr, Glycyrrhiza uralensis

Damp-heat jaundice syndrome (DHJS)

Isoformononetin, 3-O-feruloylquinic acid, Glycyrrhizic acid, Oxyberberine, Obaculactone

[87]

Ke Luo Xin

(KLX)

Astragalus L, Pseudostellaria radix, Fructus Ligustri Lucidi, Lycii Fructus, Rhei Radix et Rhizoma, Hirudo nipponica Whitman

Diabetic retinopathy (DR)

Emodin, Rhein, Astragaloside IV (AS-IV), Chrysophanol, Chrysophanol-8-O-β-D-glucopyranoside, Aloe-emodin, Aloin, Biochanin A, 10-hydroxyoleuropein, 3,4′,7-trihydroxyflavone and 3′-O-methyl-( −)-epicatechin 7-O-glucuronide (3′ME7G)

[88]

Yin Chen Hao

Tang

(YCHT)

ArtemisiacapillarisThunb, Gardeniae Fructus, Rheum officinale

Dampness-heat jaundice syndrome (DHJS)

Geniposide, Scoparone, Isorhamnetin, Quercetin, Naringenin, Rhein, Chlorogenic acid and Kaempferol

[83]

Shuanghuanglian

Formula

(SF)

Flos lonicerae japonicae, Radix scutellariae, Fructus forsythiae

Viral or bacterial infections

A total of 68 ions of interest (39 prototype components and 29 metabolites of SF) were extracted and identified from blood samples

[89]

Sijunzi decoction (SJZD)

Radix Ginseng, macrocephala, poria, licorice

Spleen qi deficiency syndrome (SQDS)

Liquirtin, Formononetin, Malonyl-ginsenoside Rb2, Ginsenoside Ro, Glycyrrhetnic acid, Glycyrrhizic acid, 2-atractylenolide, Dehydrotumulosic acid and Isoglabrolide

[64]

Wen Xin Fang

(WXF)

Codonopsis Radix, PolygonatiRhizoma, Notoginseng Radix Et Rhizoma, Ambrum, Nardostachyos Radix Et Rhizoma

Cardiac disease

Syringic acid, Damascenone, Paeoniflorin, Cinnamic acid, Berberrubine-O-glucuronide, Berberine, Ginsenoside Rb1 and Acetylbenzoyl

[90]