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Fig. 3 | Chinese Medicine

Fig. 3

From: Formononetin reverses Treg/Th17 imbalance in immune-mediated bone marrow failure mice by regulating the PI3K/Akt signaling pathway

Fig. 3

Effects of FMN on the proportion of Treg cells and Th17 cells in the bone marrow and spleen of the immune-mediated BMF mice (n = 4). A, B The proportion of Treg cells in the bone marrow was assessed using flow cytometry. C, D The proportion of Th17 cells in the bone marrow was assessed using flow cytometry. E, F The proportion of Treg cells in the spleen was evaluated using flow cytometry. G, H The proportion of Th17 cells in the spleen was evaluated using flow cytometry. I The ratio of Treg/Th17 cells in in the bone marrow and spleen of the immune-mediated BMF mice. J, K The expression levels of Foxp3 in the bone marrow were determined using immunohistochemical analysis (400 ×). L, M: The expression levels of Foxp3 in the spleen were determined by western blotting. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with the model group. #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 compared with the control group

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