Fig. 6

Effect of FMN on the PI3K/Akt signaling pathway in the immune-mediated BMF mouse model (n = 3). A Cluster analysis of GEO datasets. B: Molecular docking of FMN with PI3K. C, D: The expression levels of PI3K, p-PI3K, Akt, and p-Akt in different groups were evaluated using western blotting. E, F The expression levels of PI3K and Akt in bone marrow were detected by immunohistochemical analysis (400 ×). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with the model group. #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 compared with the control group