Fig. 1

Juglone inhibits cell proliferation and promotes cell apoptosis in GBM cells. A The 3D chemical structures of juglone. B The CCK-8 assay was used to assess the cell viabilities of LN229 and T98G cells exposed to varying concentrations and durations of juglone exposure. C, D The LN229 and T98G cells were treated with different concentrations of juglone for 14 days, the clone formation and quantitative analyses were examined. E, F The LN229 and T98G cells were treated with juglone for 24 h, the Ki67 positivity rates in drug groups at different concentrations by immunofluorescence detection. *p < 0.05;***p < 0.001