Fig. 6
Fer-1 successfully reversed the tumor suppression of juglone in vivo. The condition of Xenograft model in nude mice treated with intraperitoneal injection of either physiological saline, juglone (1 mg/kg), Fer-1 (10-mg/kg/d), or Fer-1 (10-mg/kg/d) + juglone (1 mg/kg) respectively. A Tumor-bearing mice in each group at 24th days. B, C The changes in body weight and tumor volume of nude mice are shown in each group. D The representative images of burdened tumors in each group. E–G Measure the weight of the subcutaneous tumor removed on the 24th day and the levels of MDA and GSH in the tissue. ***p < 0.001