Fig. 3

Proposed pathways for ganoderic acid biosynthesis. AACT actyl-CoA C-acetyltransferase, HMGS 3-hydroxy-3-methylglutaryl coenthase A synthase, HMGR 3-hydroxy-3-methyl glutaryl coenzyme A reductase, MK mevalonate kinase, MPK phosphomevalonate kinase, MVD mevalonate pyrophosphate decarboxylase, IPP isopentenyl diphosphate, IDI diphosphateisomerase, DMAPP dimethylallyl pyrophosphate, FPS farnesyl pyrophosphate synthase, FPP farnesyl pyrophosphate, SQS squalene synthase, SE squalene epoxidase, LSS lanosterol synthase