Fig. 1
Changes in energy metabolism parameters in mice of different age groups. A PCoA plot of differences in energy metabolism in mice of different age groups measured by indirect calorimetry. Each point represents a mouse. Fitted curves and statistical analysis of VO2 (B, C), VCO2 (D, E), and EE (F, G) in mice of different age groups. Amplitude values of EE (H), phase adjustment values of EE (I), RER (J), and body weight (K) in mice of different age groups. n = 3–4. Data are presented as mean ± standard deviation. * indicates significant differences compared to the 6w data. *p < 0.05, **p < 0.01, ***p < 0.001