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Fig. 3 | Chinese Medicine

Fig. 3

From: Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder

Fig. 3

DSD attenuated OXA-induced metabolic alterations. A Volcano plots showing differential metabolites under two comparison strategies. B Venn plot showing overlapping differential metabolites under two comparison strategies. C Bubble plots showing the most relevant pathways co-enriched by the differential metabolites. D Relative abundance of critical and prominent secondary metabolites associated with the most relevant metabolic pathways in the three groups, expressed as relative increase. E GC–MS analysis of SCFAs (acetic acid, butyric acid, valeric acid, and decanoic acid) in feces. F Heatmap of Spearman’s correlation between DSD-adjusted gut microbiota and regulated metabolites. *P < 0.05, **P < 0.01, vs. OXA group; n = 6 in every group

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