Jones DP: Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol. 2002, 348: 93-112.
Article
CAS
PubMed
Google Scholar
Jonas CR, Ziegler TR, Gu LH, Jones DP: Extracellular thiol/disulfide redox state affects proliferation rate in a human colon carcinoma (Caco2) cell line. Free Radic Biol Med. 2002, 33: 1499-1506.
Article
CAS
PubMed
Google Scholar
Yang MS, Yu LC, Gupta RC: Analysis of changes in energy and redox states in HepG2 hepatoma and C6 glioma cells upon exposure to cadmium. Toxicology. 2004, 201: 105-113.
Article
CAS
PubMed
Google Scholar
Andersson A, Lindgren A, Arnadottir M, Prytz H, Hultberg B: Thiols as a measure of plasma redox status in healthy subjects and in patients with renal or liver failure. Clin Chem. 1999, 45: 1084-1086.
CAS
PubMed
Google Scholar
Hultberg B, Andersson A, Isaksson A: Thiol and redox reactive agents exert different effects on glutathione metabolism in HeLa cell cultures. Clin Chim Acta. 1999, 283: 21-32.
Article
CAS
PubMed
Google Scholar
Menon SG, Goswami PC: A redox cycle within the cell cycle: ring in the old with the new. Oncogene. 2007, 26: 1101-1109.
Article
CAS
PubMed
Google Scholar
De Flora S, Izzotti A, D'Agostini F, Balansky RM: Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points. Carcinogenesis. 2001, 22: 999-1013.
Article
CAS
PubMed
Google Scholar
Lin T, Yang MS: Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells. Toxicology. 2007, 235: 1-10.
Article
CAS
PubMed
Google Scholar
Fisher JC, Kling DE, Kinane TB, Schnitzer JJ: Oxidation-reduction (redox) controls fetal hypoplastic lung growth. J Surg Res. 2002, 106: 287-291.
Article
CAS
PubMed
Google Scholar
Hoffman A, Spetner LM, Burke M: Cessation of cell proliferation by adjustment of cell redox potential. J Theor Biol. 2001, 211: 403-407.
Article
CAS
PubMed
Google Scholar
Kim KY, Rhim T, Choi I, Kim SS: N-acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity. J Biol Chem. 2001, 276: 40591-40598.
Article
CAS
PubMed
Google Scholar
Menon SG, Sarsour EH, Spitz DR, Higashikubo R, Sturm M, Zhang H, Goswami PC: Redox regulation of the G1 to S phase transition in the mouse embryo fibroblast cell cycle. Cancer Res. 2003, 63: 2109-2117.
CAS
PubMed
Google Scholar
Nkabyo YS, Ziegler TR, Gu LH, Watson WH, Jones DP: Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells. Am J Physiol Gastrointest Liver Physiol. 2002, 283: G1352-G1359.
Article
CAS
PubMed
Google Scholar
Sekharam M, Trotti A, Cunnick JM, Wu J: Suppression of fibroblast cell cycle progression in G1 phase by N-acetylcysteine. Toxicol Appl Pharmacol. 1998, 149: 210-216.
Article
CAS
PubMed
Google Scholar
Burdon RH, Gill V, Rice-Evans C: Oxidative stress and tumour cell proliferation. Free Radic Res Commun. 1990, 11: 65-76.
Article
CAS
PubMed
Google Scholar
Kusano C, Takao S, Noma H, Yoh H, Aikou T, Okumura H, Akiyama S, Kawamura M, Makino M, Baba M: N-acetyl cysteine inhibits cell cycle progression in pancreatic carcinoma cells. Hum Cell. 2000, 13: 213-220.
CAS
PubMed
Google Scholar
Menon SG, Coleman MC, Walsh SA, Spitz DR, Goswami PC: Differential susceptibility of nonmalignant human breast epithelial cells and breast cancer cells to thiol antioxidant-induced G(1)-delay. Antioxid Redox Signal. 2005, 7: 711-718.
Article
CAS
PubMed
Google Scholar
Burdon RH, Rice-Evans C: Free radicals and the regulation of mammalian cell proliferation. Free Radic Res Commun. 1989, 6: 345-358.
Article
CAS
PubMed
Google Scholar
Burdon RH, Gill V, Rice-Evans C: Cell proliferation and oxidative stress. Free Radic Res Commun. 1989, 7: 149-159.
Article
CAS
PubMed
Google Scholar
Conour JE, Graham WV, Gaskins HR: A combined in vitro/bioinformatic investigation of redox regulatory mechanisms governing cell cycle progression. Physiol Genomics. 2004, 18: 196-205.
Article
CAS
PubMed
Google Scholar
Futakuchi M, Ogawa K, Tamano S, Takahashi S, Shirai T: Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. Cancer Sci. 2004, 95: 18-24.
Article
CAS
PubMed
Google Scholar
Martin V, Herrera F, Carrera-Gonzalez P, Garcia-Santos G, Antolin I, Rodriguez-Blanco J, Rodriguez C: Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin. Cancer Res. 2006, 66: 1081-1088.
Article
CAS
PubMed
Google Scholar
Attele AS, Wu JA, Yuan CS: Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol. 1999, 58: 1685-1693.
Article
CAS
PubMed
Google Scholar
Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L, Dey L, Pugh W, Rue PA, Polonsky KS, Yuan CS: Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes. 2002, 51: 1851-1858.
Article
CAS
PubMed
Google Scholar
Yokozawa T, Satoh A, Cho EJ: Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice. J Pharm Pharmacol. 2004, 56: 107-113.
Article
CAS
PubMed
Google Scholar
Liu ZQ, Luo XY, Sun YX, Chen YP, Wang ZC: Can ginsenosides protect human erythrocytes against free-radical-induced hemolysis?. Biochim Biophys Acta. 2002, 1572: 58-66.
Article
CAS
PubMed
Google Scholar
Liu ZQ, Luo XY, Liu GZ, Chen YP, Wang ZC, Sun YX: In vitro study of the relationship between the structure of ginsenoside and its antioxidative or prooxidative activity in free radical induced hemolysis of human erythrocytes. J Agric Food Chem. 2003, 51: 2555-2558.
Article
CAS
PubMed
Google Scholar
Deng HL, Zhang JT: Anti-lipid peroxilative effect of ginsenoside Rb1 and Rg1. Chin Med J (Engl ). 1991, 104: 395-398.
CAS
Google Scholar
Chen XC, Zhou YC, Chen Y, Zhu YG, Fang F, Chen LM: Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress. Acta Pharmacol Sin. 2005, 26: 56-62.
Article
PubMed
Google Scholar
Zhang Q, Kang X, Zhao W: Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma. Biochem Biophys Res Commun. 2006, 342: 824-828.
Article
CAS
PubMed
Google Scholar
Wang W, Zhao Y, Rayburn ER, Hill DL, Wang H, Zhang R: In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng. Cancer Chemother Pharmacol. 2007, 59: 589-601.
Article
CAS
PubMed
Google Scholar
Li G, Wang Z, Sun Y, Liu K, Wang Z: Ginsenoside 20(S)-protopanaxadiol inhibits the proliferation and invasion of human fibrosarcoma HT1080 cells. Basic Clin Pharmacol Toxicol. 2006, 98: 588-592.
Article
CAS
PubMed
Google Scholar
Yokozawa T, Liu ZW, Dong E: A study of ginsenoside-Rd in a renal ischemia-reperfusion model. Nephron. 1998, 78: 201-206.
Article
CAS
PubMed
Google Scholar
Yokozawa T, Owada S: Effect of ginsenoside-Rd in cephaloridine-induced renal disorder. Nephron. 1999, 81: 200-207.
Article
CAS
PubMed
Google Scholar
Yokozawa T, Liu ZW: The role of ginsenoside-Rd in cisplatin-induced acute renal failure. Ren Fail. 2000, 22: 115-127.
Article
CAS
PubMed
Google Scholar
Yokozawa T, Dong E: Role of ginsenoside-Rd in cisplatin-induced renal injury: special reference to DNA fragmentation. Nephron. 2001, 89: 433-438.
Article
CAS
PubMed
Google Scholar
Xie JT, Shao ZH, Vanden Hoek TL, Chang WT, Li J, Mehendale S, Wang CZ, Hsu CW, Becker LB, Yin JJ, Yuan CS: Antioxidant effects of ginsenoside Re in cardiomyocytes. Eur J Pharmacol. 2006, 532: 201-207.
Article
CAS
PubMed
Google Scholar
Yue PY, Wong DY, Wu PK, Leung PY, Mak NK, Yeung HW, Liu L, Cai Z, Jiang ZH, Fan TP, Wong RN: The angiosuppressive effects of 20(R)- ginsenoside Rg3. Biochem Pharmacol. 2006, 72: 437-445.
Article
CAS
PubMed
Google Scholar
Kumar A, Kumar M, Panwar M, Samarth RM, Park TY, Park MH, Kimura H: Evaluation of chemopreventive action of Ginsenoside Rp1. Biofactors. 2006, 25: 29-43.
Article
Google Scholar
Popovich DG, Kitts DD: Ginsenosides 20(S)-protopanaxadiol and Rh2 reduce cell proliferation and increase sub-G1 cells in two cultured intestinal cell lines, Int-407 and Caco-2. Can J Physiol Pharmacol. 2004, 82: 183-190.
Article
CAS
PubMed
Google Scholar
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND: Glutathione metabolism and its implications for health. J Nutr. 2004, 134: 489-492.
CAS
PubMed
Google Scholar
Grobben B, De Deyn PP, Slegers H: Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion. Cell Tissue Res. 2002, 310: 257-270.
Article
CAS
PubMed
Google Scholar
Yang MS, Gupta RC: Determination of energy charge potential in the C6 glioma and the HepG-2 cell culture. Toxicology Mechanisms and Methods. 2003, 13: 97-101.
Article
PubMed
Google Scholar
Hissin PJ, Hilf R: A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem. 1976, 74: 214-226.
Article
CAS
PubMed
Google Scholar
Yang MS, Yu LC, S.W. P: Manipulation of energy and redox states in the C6 glioma cells by buthionine sulfoxamine and N-acetylcysteine and the effect on cell survival to cadmium toxicity. Cellular and Molecular Biology. 2007, 53: 56-61.
CAS
PubMed
Google Scholar
Shi MM, Iwamoto T, Forman HJ: gamma-Glutamylcysteine synthetase and GSH increase in quinone-induced oxidative stress in BPAEC. Am J Physiol. 1994, 267: L414-L421.
CAS
PubMed
Google Scholar
Chen ZH, Yoshida Y, Saito Y, Sekine A, Noguchi N, Niki E: Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. J Biol Chem. 2006, 281: 14440-14445.
Article
CAS
PubMed
Google Scholar
Bae EA, Shin JE, Kim DH: Metabolism of ginsenoside Re by human intestinal microflora and its estrogenic effect. Biol Pharm Bull. 2005, 28: 1903-1908.
Article
CAS
PubMed
Google Scholar
Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN: Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin Med. 2007, 2: 6-
Article
PubMed Central
PubMed
Google Scholar