Protective effect of Phellinus linteus polysaccharide extracts against thioacetamide-induced liver fibrosis in rats: a proteomics analysis

Table 2 Differentially expressed liver proteins between the TAA-induced liver fibrosis rats in the PLP and TAA groups

Spot No.¹	Protein name	GenInfo identifier²	Protein score³	Expression quantity (×10²) TAA	Expression quantity (×10²) PLP	Expression change (PLP/TAA)	P	pI ⁴	Mr(kDa)⁴
1011	actin, cytoplasmic 2	gi\|4501887	65	62.6 ± 24.5	97.1 ± 13.0	1.6	0.012	5.31	42.1
1619	tubulin alpha-1C chain	gi\|58865558	254	29.4 ± 13.0	55.4 ± 14.0	1.9	0.014	4.96	50.6
3802	hemopexin	gi\|122065203	262	100.5 ± 34.1	61.4 ± 15.4	−1.6	0.028	7.58	52.0
5011	galectin-5	gi\|785053	120	11.5 ± 9.5	75.3 ± 44.9	6.5	0.028	6.95	15.5
5514	Bckdha protein	gi\|59808237	88	41.3 ± 9.1	61.0 ± 11.5	1.5	0.008	6.4	37.6
7113	dihydrofolate reductase	gi\|18426814	100	49.3 ± 14.7	73.8 ± 14.0	1.5	0.015	6.77	21.7
7126	Glutathione S-transferase alpha-4	gi\|157820217	67	15.1 ± 7.6	28.9 ± 11.3	1.9	0.033	6.77	25.6
7203	preprohaptoglobin	gi\|204657	75	54.8 ± 20.6	92.5 ± 16.2	1.7	0.005	7.16	30.4
8005	ribonuclease UK114	gi\|47168636	159	172.2 ± 69.2	78.9 ± 45.1	−2.2	0.020	7.79	14.4
8110	quinoid dihydropteridine reductase, isoform CRA_c	gi\|149047263	135	83.7 ± 22.3	128.5 ± 25.5	1.5	0.009	9.69	27.9
8207	betaine-homocysteine S-methyltransferase 1	gi\|13540663	142	128.6 ± 42.6	65.1 ± 12	−2.0	0.006	8.02	45.4
8305	glyceraldehyde-3-phosphate dehydrogenase	gi\|8393418	130	141.6 ± 69.1	225.8 ± 44.3	1.6	0.035	8.14	36.1
9308	thiosulfate sulfurtransferase	gi\|57528682	256	63.8 ± 15.7	99.7 ± 22.8	1.6	0.010	7.71	33.6

¹Spot no.: automatically assigned by the PDQuest software.
²GenInfo identifier: sequence identification number assigned by GenBank.
³Protein score: generated by the MS identification system.
⁴Mr and pI: relative molecular mass (Mr) and isoelectric point (pI) generated by the MS system.

ISSN: 1749-8546