Fig. 6

EA relieved mechanical allodynia, visceral hyperalgesia and depression-like behaviors in IBD mice. a Experimental flowchart. b Time course of mechanical threshold after EA treatment. c Visceral hyperalgesia was evaluated by CRD. d After EA treatment, mice’s preference for sucrose was recorded as: sucrose consumption(g)/(sucrose consumption(g) + water consumption(g)) × 100%. e Representative results of the effect of the EA treatment on the proportion of floating time in the FST. The proportion of floating time was recorded as: (Floating time(s) / total time(s)) × 100%. f Representative results of the effect of the EA treatment on the proportion of immobility time in the TST. The proportion of immobility time was recorded as: (Immobility time(s)/total time(g)) × 100%. The data are expressed as mean ± SEM (n = 7–10 mice). *p < 0.05, compared with the control group; ^#p < 0.05, compared with the TNBS group; ^Δp < 0.05, compared with the EA group