Table 1 Matrix effects of SHL samples on mass spectrometric detection of the IS
From: Metabolomics analyses of traditional Chinese medicine formula Shuang Huang Lian by UHPLC-QTOF-MS/MS
SHL sample | ESI mode | PAISa in extracted sample matrix ± SDb | PAIS in solution ± SD | MFISc ± SD |
|---|---|---|---|---|
Granules | + | (6.95 ± 0.05) × 105 | (7.6 ± 0.2) × 105 | 0.91 ± 0.02 |
− | (2.05 ± 0.08) × 106 | (2.2 ± 0.1) × 106 | 0.93 ± 0.06 | |
Oral liquid | + | (7.4 ± 0.2) × 105 | (7.6 ± 0.2) × 105 | 0.97 ± 0.04 |
− | (2.09 ± 0.02) × 106 | (2.2 ± 0.1) × 106 | 0.95 ± 0.04 | |
Tablet | + | (7.1 ± 0.1) × 105 | (7.6 ± 0.2) × 105 | 0.93 ± 0.03 |
− | (1.96 ± 0.05) × 106 | (2.2 ± 0.1) × 106 | 0.89 ± 0.05 |