Siddiqui IA, Adhami VM, Bharali DJ, Hafeez BB, Asim M, Khwaja SI, et al. Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate. Cancer Res. 2009;69(5):1712–6.
CAS
PubMed
PubMed Central
Google Scholar
Heleno SA, Martins A, Queiroz MJRP, Ferreira ICFR. Bioactivity of phenolic acids: metabolites versus parent compounds—a review. Food Chem. 2015;173:501–13.
CAS
PubMed
Google Scholar
Li Z, Jiang H, Xu C, Gu L. A review: using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals. Food Hydrocoll. 2015;43:153–64.
CAS
Google Scholar
Khan H, Mirzaei HR, Amiri A, Kupeli Akkol E, Ashhad Halimi SM, Mirzaei H. Glyco-nanoparticles: new drug delivery systems in cancer therapy. Semin Cancer Biol. 2021;69:24–42.
CAS
PubMed
Google Scholar
Sun Y, Jing X, Ma X, Feng Y, Hu H. Versatile types of polysaccharide-based drug delivery systems: from strategic design to cancer therapy. Int J Mol Sci. 2020. https://doi.org/10.3390/ijms21239159.
Article
PubMed
PubMed Central
Google Scholar
Bian Y, Zeng H, Tao H, Huang L, Du Z, Wang J, et al. A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy. Int J Biol Macromol. 2020;162:107–15.
CAS
PubMed
Google Scholar
Cui L, Chen L, Yang G, Li Y, Qiao Z, Liu Y, et al. Structural characterization and immunomodulatory activity of a heterogalactan from Panax ginseng flowers. Food Res Int. 2021;140: 109859.
CAS
PubMed
Google Scholar
Guo C, Wang Y, Zhang S, Zhang X, Du Z, Li M, et al. Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism. Int J Biol Macromol. 2021;181:357–68.
CAS
PubMed
Google Scholar
Liu Z, Jiao Y, Wang Y, Zhou C, Zhang Z. Polysaccharides-based nanoparticles as drug delivery systems. Adv Drug Deliv Rev. 2008;60(15):1650–62.
CAS
PubMed
Google Scholar
Ghumman SA, Bashir S, Noreen S, Khan AM, Riffat S, Abbas M. Polymeric microspheres of okra mucilage and alginate for the controlled release of oxcarbazepine: in vitro and in vivo evaluation. Int J Biol Macromol. 2018;111:1156–65.
CAS
PubMed
Google Scholar
Wu Y, Zhang W, Huang J, Luo Z, Li J, Wang L, et al. Mucoadhesive improvement of alginate microspheres as potential gastroretentive delivery carrier by blending with Bletilla striata polysaccharide. Int J Biol Macromol. 2020;156:1191–201.
CAS
PubMed
Google Scholar
Zheng Y, Xie Q, Wang H, Hu Y, Ren B, Li X. Recent advances in plant polysaccharide-mediated nano drug delivery systems. Int J Biol Macromol. 2020;165(Pt B):2668–83.
CAS
PubMed
Google Scholar
Saravanakumar G, Jo DG, Park JH. Polysaccharide-based nanoparticles: a versatile platform for drug delivery and biomedical imaging. Curr Med Chem. 2012;19(19):3212–29.
CAS
PubMed
Google Scholar
Thambi T, Park JH. Recent advances in shell-sheddable nanoparticles for cancer therapy. J Biomed Nanotechnol. 2014;10(9):1841–62.
CAS
PubMed
Google Scholar
Shen H, Gao XJ, Li T, Jing WH, Han BL, Jia YM, et al. Ginseng polysaccharides enhanced ginsenoside Rb1 and microbial metabolites exposure through enhancing intestinal absorption and affecting gut microbial metabolism. J Ethnopharmacol. 2018;216:47–56.
CAS
PubMed
Google Scholar
Zheng D, Zhao J, Tao Y, Liu J, Wang L, He J, et al. pH and glutathione dual responsive nanoparticles based on Ganoderma lucidum polysaccharide for potential programmable release of three drugs. Chem Eng J. 2020;389: 124418.
CAS
Google Scholar
Zhou B, Zhang W, Wu Y, Yang Y, Wang N, Li J, et al. Improved efficacy of Panax notoginseng saponin loaded into BSP/alginate microspheres for the treatment of alcoholic gastric ulcers. Int J Pharm. 2021;596: 120218.
CAS
PubMed
Google Scholar
Yang J, Han S, Zheng H, Dong H, Liu J. Preparation and application of micro/nanoparticles based on natural polysaccharides. Carbohydr Polym. 2015;123:53–66.
CAS
PubMed
Google Scholar
Kumar K, Dhawan N, Sharma H, Vaidya S, Vaidya B. Bioadhesive polymers: novel tool for drug delivery. Artif Cells Nanomed Biotechnol. 2014;42(4):274–83.
CAS
PubMed
Google Scholar
Sharma HK, Lahkar S, Kanta NL. Formulation and in vitro evaluation of metformin hydrochloride loaded microspheres prepared with polysaccharide extracted from natural sources. Acta Pharm. 2013;63(2):209–22.
CAS
PubMed
Google Scholar
Kalhapure RS, Renukuntla J. Thermo- and pH dual responsive polymeric micelles and nanoparticles. Chem Biol Interact. 2018;295:20–37.
CAS
PubMed
Google Scholar
Gong C, Wei X, Wang X, Wang Y, Guo G, Mao Y, et al. Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic honokiol delivery: I Preparation and characterization. Nanotechnology. 2010;21(21): 215103.
PubMed
Google Scholar
Bu X, Ji N, Dai L, Dong X, Chen M, Xiong L, et al. Self-assembled micelles based on amphiphilic biopolymers for delivery of functional ingredients. Trends Food Sci Technol. 2021;114:386–98.
CAS
Google Scholar
Wei Z, Huang Q. Assembly of protein-polysaccharide complexes for delivery of bioactive ingredients: a perspective paper. J Agric Food Chem. 2019;67(5):1344–52.
CAS
PubMed
Google Scholar
Chen Z, Cheng L, He Y, Wei X. Extraction, characterization, utilization as wound dressing and drug delivery of Bletilla striata polysaccharide: a review. Int J Biol Macromol. 2018;120(Pt B):2076–85.
CAS
PubMed
Google Scholar
Wang L, Wu Y, Li J, Qiao H, Di L. Rheological and mucoadhesive properties of polysaccharide from Bletilla striata with potential use in pharmaceutics as bio-adhesive excipient. Int J Biol Macromol. 2018;120(Pt A):529–36.
CAS
PubMed
Google Scholar
Peng Q, Li M, Xue F, Liu H. Structure and immunobiological activity of a new polysaccharide from Bletilla striata. Carbohydr Polym. 2014;107:119–23.
CAS
PubMed
Google Scholar
He X, Wang X, Fang J, Zhao Z, Huang L, Guo H, et al. Bletilla striata: medicinal uses, phytochemistry and pharmacological activities. J Ethnopharmacol. 2017;195:20–38.
CAS
PubMed
Google Scholar
Li JY, Kuang MT, Yang L, Kong QH, Hou B, Liu ZH, et al. Stilbenes with anti-inflammatory and cytotoxic activity from the rhizomes of Bletilla ochracea Schltr. Fitoterapia. 2018;127:74–80.
CAS
PubMed
Google Scholar
Zhang X, Jackson JK, Burt HM. Development of amphiphilic diblock copolymers as micellar carriers of taxol. Int J Pharm. 1996;132(1):195–206.
CAS
Google Scholar
Zhao L, Sun D, Lu H, Han B, Zhang G, Guan Q. In vitro characterization of pH-sensitive Bletilla striata polysaccharide copolymer micelles and enhanced tumour suppression in vivo. J Pharm Pharmacol. 2018;70(6):797–807.
CAS
PubMed
Google Scholar
Ma Y, He S, Ma X, Hong T, Li Z, Park K, et al. Silymarin-loaded nanoparticles based on stearic acid-modified Bletilla striata polysaccharide for hepatic targeting. Molecules. 2016;21(3):265.
PubMed
PubMed Central
Google Scholar
Yi C, Luo Z, Lu Y, Belwal T, Pan X, Lin X. Nanoporous hydrogel for direct digital nucleic acid amplification in untreated complex matrices for single bacteria counting. Biosens Bioelectron. 2021;184: 113199.
CAS
PubMed
Google Scholar
Piao Y, Chen B. Synthesis and mechanical properties of double cross-linked gelatin-graphene oxide hydrogels. Int J Biol Macromol. 2017;101:791–8.
CAS
PubMed
Google Scholar
Li H, Zhao L, Chen XD, Mercadé-Prieto R. Swelling of whey and egg white protein hydrogels with stranded and particulate microstructures. Int J Biol Macromol. 2016;83:152–9.
CAS
PubMed
Google Scholar
Ren H, Wang L, Bao H, Xia Y, Xu D, Zhang W, et al. Improving the antibacterial property of chitosan hydrogel wound dressing with licorice polysaccharide. J Renew Mater. 2020;8(10):1343–55.
CAS
Google Scholar
Singh B, Bala R. Polysaccharide based hydrogels as controlled drug delivery system for GIT cancer. Int J Biol Macromol. 2014;65:524–33.
CAS
PubMed
Google Scholar
Jiang J, Wu C, Gao H, Song J, Li H. Effects of astragalus polysaccharides on immunologic function of erythrocyte in chickens infected with infectious bursa disease virus. Vaccine. 2010;28(34):5614–6.
CAS
PubMed
Google Scholar
Li K, Li S, Du Y, Qin X. Screening and structure study of active components of Astragalus polysaccharide for injection based on different molecular weights. J Chromatogr B Analyt Technol Biomed Life Sci. 2020;1152: 122255.
CAS
PubMed
Google Scholar
Yan J, Wang Y, Zhang X, Zhao X, Ma J, Pu X, et al. Snakegourd root/Astragalus polysaccharide hydrogel preparation and application in 3D printing. Int J Biol Macromol. 2019;121:309–16.
CAS
PubMed
Google Scholar
Huang Y, Shi F, Wang L, Yang Y, Khan BM, Cheong K-L, et al. Preparation and evaluation of Bletilla striata polysaccharide/carboxymethyl chitosan/Carbomer 940 hydrogel for wound healing. Int J Biol Macromol. 2019;132:729–37.
CAS
PubMed
Google Scholar
Gavini E, Bonferoni CM, Rassu G, Obinu A, Ferrari F, Giunchedi P. Biodegradable microspheres as intravitreal delivery systems for prolonged drug release. What is their eminence in the nanoparticle era? Curr Drug Deliv. 2018;15(7):930–40.
CAS
PubMed
Google Scholar
Patil H, Tiwari RV, Repka MA. Recent advancements in mucoadhesive floating drug delivery systems: a mini-review. J Drug Deliv Sci Tec. 2016;31:65–71.
CAS
Google Scholar
Zhang X, Hui Z, Wan D, Huang H, Huang J, Yuan H, et al. Alginate microsphere filled with carbon nanotube as drug carrier. Int J Biol Macromol. 2010;47(3):389–95.
CAS
PubMed
Google Scholar
Wang K, Xu J, Liu Y, Cui Z, He Z, Zheng Z, et al. Self-assembled Angelica sinensis polysaccharide nanoparticles with an instinctive liver-targeting ability as a drug carrier for acute alcoholic liver damage protection. Int J Pharm. 2020;577: 118996.
CAS
PubMed
Google Scholar
Xuchen L, Guang B. In vivo and in vitro effects of Bletilla striata polysaccharide-loaded paclitaxel nanoparticles on human gastric cancer cells. Trop J Pharm Res. 2019;18:13.
Google Scholar
Liu Y, Wu J, Huang L, Qiao J, Wang N, Yu D, et al. Synergistic effects of antitumor efficacy via mixed nano-size micelles of multifunctional Bletilla striata polysaccharide-based copolymer and D-α-tocopheryl polyethylene glycol succinate. Int J Biol Macromol. 2020;154:499–510.
CAS
PubMed
Google Scholar
Zhang G, Wu J, Liu Y, Huang L, Qiao J, Liu X, et al. Effects of degree of substitution on stearic acid-modified Bletilla striata polysaccharides nanoparticles and interactions between nanoparticles and bovine serum albumin. Chin Chem Lett. 2018;29(12):1861–4.
CAS
Google Scholar
Masci A, Carradori S, Casadei MA, Paolicelli P, Petralito S, Ragno R, et al. Lycium barbarum polysaccharides: extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects—a review. Food Chem. 2018;254:377–89.
CAS
PubMed
Google Scholar
Yu YS, Luo M, Zhu DH. The effect of quality attributes on visiting consumers’ patronage intentions of green restaurants. Sustainability. 2018;10(4):1187.
Google Scholar
Wang Y, Han Q, Bai F, Luo Q, Wu M, Song G, et al. The assembly and antitumor activity of lycium barbarum polysaccharide-platinum-based conjugates. J Inorg Biochem. 2020;205: 111001.
CAS
PubMed
Google Scholar
Chen L, Wang Z, Zhang B, Ge M, Ng H, Niu Y, et al. Production, structure and morphology of exopolysaccharides yielded by submerged fermentation of Antrodia cinnamomea. Carbohydr Polym. 2019;205:271–8.
CAS
PubMed
Google Scholar
Zhang Y, Zhou T, Wang H, Cui Z, Cheng F, Wang KP. Structural characterization and in vitro antitumor activity of an acidic polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydr Polym. 2016;147:401–8.
CAS
PubMed
Google Scholar
Zhang Y, Tang J, Li M, Shu Y, Wang F, Cao W, et al. Enhancing the biological activity of vaterite-containing β-dicalcium silicate cement by silane coupling agent for biomaterials. Mater Sci Eng C. 2018;92:1–10.
CAS
Google Scholar
Nai J, Zhang C, Shao H, Li B, Li H, Gao L, et al. Extraction, structure, pharmacological activities and drug carrier applications of Angelica sinensis polysaccharide. Int J Biol Macromol. 2021;183:2337–53.
CAS
PubMed
Google Scholar
Zhang Y, Cui Z, Mei H, Xu J, Zhou T, Cheng F, et al. Angelica sinensis polysaccharide nanoparticles as a targeted drug delivery system for enhanced therapy of liver cancer. Carbohydr Polym. 2019;219:143–54.
CAS
PubMed
Google Scholar
Wang M, Huang M, Wang J, Ye M, Deng Y, Li H, et al. Facile one-pot synthesis of self-assembled folate-biotin-pullulan nanoparticles for targeted intracellular anticancer drug delivery. J Nanomater. 2016;2016:1–10.
Google Scholar
Shen S, Li H, Yang W. The preliminary evaluation on cholesterol-modified pullulan as a drug nanocarrier. Drug Deliv. 2014;21(7):501–8.
CAS
PubMed
Google Scholar
Liu Y, Sun C, Zhang G, Wu J, Huang L, Qiao J, et al. Bio-responsive Bletilla striata polysaccharide-based micelles for enhancing intracellular docetaxel delivery. Int J Biol Macromol. 2020;142:277–87.
CAS
PubMed
Google Scholar
Guan Q, Sun D, Zhang G, Sun C, Wang M, Ji D, et al. Docetaxel-loaded self-assembly stearic acid-modified Bletilla striata polysaccharide micelles and their anticancer effect: preparation, characterization, cellular uptake and in vitro evaluation. Molecules. 2016;21(12):1641.
CAS
PubMed Central
Google Scholar
Bao Y, Guo Y, Zhuang X, Li D, Cheng B, Tan S, et al. d-α-tocopherol polyethylene glycol succinate-based redox-sensitive paclitaxel prodrug for overcoming multidrug resistance in cancer cells. Mol Pharm. 2014;11(9):3196–209.
CAS
PubMed
Google Scholar
Zeng P, Guo Z, Zeng X, Hao C, Zhang Y, Zhang M, et al. Chemical, biochemical, preclinical and clinical studies of Ganoderma lucidum polysaccharide as an approved drug for treating myopathy and other diseases in China. J Cell Mol Med. 2018;22(7):3278–97.
PubMed
PubMed Central
Google Scholar
Zhao Y, Wan P, Wang J, Li P, Hu Q, Zhao R. Polysaccharide from vinegar baked radix bupleuri as efficient solubilizer for water-insoluble drugs of Chinese medicine. Carbohydr Polym. 2020;229: 115473.
CAS
PubMed
Google Scholar
Sun LL, Wang M, Zhang HJ, You GJ, Liu YN, Ren XL, et al. The influence of polysaccharides from Ophiopogon japonicus on 2,3,5,4′-tetrahydroxy-stilbene-2-O-β-d-glucoside about biopharmaceutical properties in vitro and pharmacokinetics in vivo. Int J Biol Macromol. 2018;119:677–82.
CAS
PubMed
Google Scholar
Liu F, Sun L, You G, Liu H, Ren X, Wang M. Effects of Astragalus polysaccharide on the solubility and stability of 15 flavonoids. Int J Biol Macromol. 2020;143:873–80.
CAS
PubMed
Google Scholar
Cao X, Wang L, Liu M, Ren X, Han T, Deng Y. Study on solubilization and stabilization of eight flavonoids by 17 Chinese herbal polysaccharides. J Chem. 2020;2020:1–10.
Google Scholar
Guo Q, Ma Q, Xue Z, Gao X, Chen H. Studies on the binding characteristics of three polysaccharides with different molecular weight and flavonoids from corn silk (Maydis stigma). Carbohydr Polym. 2018;198:581–8.
CAS
PubMed
Google Scholar
Song X, Ren T, Zheng Z, Lu T, Wang Z, Du F, et al. Anti-tumor and immunomodulatory activities induced by an alkali-extracted polysaccharide BCAP-1 from Bupleurum chinense via NF-κB signaling pathway. Int J Biol Macromol. 2017;95:357–62.
CAS
PubMed
Google Scholar
Hu B, Xie M, Zhang C, Zeng X. Genipin-structured peptide-polysaccharide nanoparticles with significantly improved resistance to harsh gastrointestinal environments and their potential for oral delivery of polyphenols. J Agric Food Chem. 2014;62(51):12443–52.
CAS
PubMed
Google Scholar
Gu J, Zhang H, Yao H, Zhou J, Duan Y, Ma H. Comparison of characterization, antioxidant and immunological activities of three polysaccharides from Sagittaria sagittifolia L. Carbohydr Polym. 2020;235: 115939.
CAS
PubMed
Google Scholar
Simayi Z, Rozi P, Yang X, Ababaikeri G, Maimaitituoheti W, Bao X, et al. Isolation, structural characterization, biological activity, and application of Glycyrrhiza polysaccharides: systematic review. Int J Biol Macromol. 2021;183:387–98.
CAS
PubMed
Google Scholar
Cai Z, Dai Q, Guo Y, Wei Y, Wu M, Zhang H. Glycyrrhiza polysaccharide-mediated synthesis of silver nanoparticles and their use for the preparation of nanocomposite curdlan antibacterial film. Int J Biol Macromol. 2019;141:422–30.
CAS
PubMed
Google Scholar
Ding L, Huang Y, Cai X, Wang S. Impact of pH, ionic strength and chitosan charge density on chitosan/casein complexation and phase behavior. Carbohydr Polym. 2019;208:133–41.
CAS
PubMed
Google Scholar
Fan Y, Yi J, Zhang Y, Yokoyama W. Fabrication of curcumin-loaded bovine serum albumin (BSA)-dextran nanoparticles and the cellular antioxidant activity. Food Chem. 2018;239:1210–8.
CAS
PubMed
Google Scholar
Zhang L, Zhang F, Fang Y, Wang S. Alginate-shelled SPI nanoparticle for encapsulation of resveratrol with enhanced colloidal and chemical stability. Food Hydrocoll. 2019;90:313–20.
CAS
Google Scholar
Feng J, Wu S, Wang H, Liu S. Improved bioavailability of curcumin in ovalbumin-dextran nanogels prepared by Maillard reaction. J Funct Foods. 2016;27:55–68.
CAS
Google Scholar
Yi J, Lam TI, Yokoyama W, Cheng LW, Zhong F. Controlled Release of β-carotene in β-lactoglobulin–dextran-conjugated nanoparticles’ in vitro digestion and transport with Caco-2 monolayers. J Agric Food Chem. 2014;62(35):8900–7.
CAS
PubMed
Google Scholar
Yang Q, Huang M, Cai X, Jia L, Wang S. Investigation on activation in RAW264.7 macrophage cells and protection in cyclophosphamide-treated mice of Pseudostellaria heterophylla protein hydrolysate. Food Chem Toxicol. 2019;134: 110816.
CAS
PubMed
Google Scholar
Cai X, Yang Q, Weng Q, Wang S. pH sensitive doxorubicin-loaded nanoparticle based on Radix pseudostellariae protein-polysaccharide conjugate and its improvement on HepG2 cellular uptake of doxorubicin. Food Chem Toxicol. 2020;136: 111099.
CAS
PubMed
Google Scholar
Mao L, Lu Y, Cui M, Miao S, Gao Y. Design of gel structures in water and oil phases for improved delivery of bioactive food ingredients. Crit Rev Food Sci Nutr. 2020;60(10):1651–66.
CAS
PubMed
Google Scholar
Yang L, Han Z, Chen C, Li Z, Yu S, Qu Y, et al. Novel probiotic-bound oxidized Bletilla striata polysaccharide-chitosan composite hydrogel. Mater Sci Eng C. 2020;117: 111265.
CAS
Google Scholar
Ding W, Wang YN, Zhou J, Shi B. Effect of structure features of polysaccharides on properties of dialdehyde polysaccharide tanning agent. Carbohydr Polym. 2018;201:549–56.
CAS
PubMed
Google Scholar
Fang L, Lin H, Wu Z, Wang Z, Fan X, Cheng Z, et al. In vitro/vivo evaluation of novel mitochondrial targeting charge-reversal polysaccharide-based antitumor nanoparticle. Carbohydr Polym. 2020;234: 115930.
CAS
PubMed
Google Scholar
Li H, Dong L, Liu Y, Wang G, Wang G, Qiao Y. Biopharmaceutics classification of puerarin and comparison of perfusion approaches in rats. Int J Pharm. 2014;466(1):133–8.
CAS
PubMed
Google Scholar
Fang J, Wang X, Lu M, He X, Yang X. Recent advances in polysaccharides from Ophiopogon japonicus and Liriope spicata var. prolifera. Int J Biol Macromol. 2018;114:1257–66.
CAS
PubMed
Google Scholar
Beneke C, Viljoen A, Hamman J. In vitro drug absorption enhancement effects of aloe vera and aloe ferox. Sci Pharm. 2012. https://doi.org/10.3797/scipharm.1202-10.
Article
PubMed
PubMed Central
Google Scholar
Carien B, Alvaro V, Josias H. Modulation of drug efflux by aloe materials: an in vitro investigation across rat intestinal tissue. Pharmacogn Mag. 2013;9(Suppl 1):S44–8.
PubMed
PubMed Central
Google Scholar
Tian QE, Li HD, Yan M, Cai HL, Tan QY, Zhang WY. Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice. World J Gastroenterol. 2012;18(47):7079–86.
CAS
PubMed
PubMed Central
Google Scholar
Meng Y, Zhang Y, Jia N, Qiao H, Zhu M, Meng Q, et al. Synthesis and evaluation of a novel water-soluble high Se-enriched Astragalus polysaccharide nanoparticles. Int J Biol Macromol. 2018;118:1438–48.
CAS
PubMed
Google Scholar
Cui D, Ma J, Liang T, Sun L, Meng L, Liang T, et al. Selenium nanoparticles fabricated in laminarin polysaccharides solutions exert their cytotoxicities in HepG2 cells by inhibiting autophagy and promoting apoptosis. Int J Biol Macromol. 2019;137:829–35.
CAS
PubMed
Google Scholar
Indermun S, Luttge R, Choonara YE, Kumar P, du Toit LC, Modi G, et al. Current advances in the fabrication of microneedles for transdermal delivery. J Control Release. 2014;185:130–8.
CAS
PubMed
Google Scholar
Serrano-Castañeda P, Escobar-Chavez JJ, Rodriguez-Cruz IM, Melgoza LM, Martinez-Hernandez J. Microneedles as enhancer of drug absorption through the skin and applications in medicine and cosmetology. J Pharm Pharm Sci. 2018;21(1):73–93.
PubMed
Google Scholar
Cheung K, Das DB. Microneedles for drug delivery: trends and progress. Drug Deliv. 2016;23(7):2338–54.
CAS
PubMed
Google Scholar
Hu L, Liao Z, Hu Q, Maffucci KG, Qu Y. Novel Bletilla striata polysaccharide microneedles: fabrication, characterization, and in vitro transcutaneous drug delivery. Int J Biol Macromol. 2018;117:928–36.
CAS
PubMed
Google Scholar
Kim S, Lee J, Shayan FL, Kim S, Huh I, Ma Y, et al. Physicochemical study of ascorbic acid 2-glucoside loaded hyaluronic acid dissolving microneedles irradiated by electron beam and gamma ray. Carbohydr Polym. 2018;180:297–303.
CAS
PubMed
Google Scholar
Lee SG, Jeong JH, Lee KM, Jeong KH, Yang H, Kim M, et al. Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule. Int J Nanomedicine. 2014;9:289–99.
PubMed
Google Scholar
Loizidou EZ, Williams NA, Barrow DA, Eaton MJ, McCrory J, Evans SL, et al. Structural characterisation and transdermal delivery studies on sugar microneedles: experimental and finite element modelling analyses. Eur J Pharm Biopharm. 2015;89:224–31.
CAS
PubMed
Google Scholar
Ding L, Shan X, Zhao X, Zha H, Chen X, Wang J, et al. Spongy bilayer dressing composed of chitosan–Ag nanoparticles and chitosan–Bletilla striata polysaccharide for wound healing applications. Carbohydr Polym. 2017;157:1538–47.
CAS
PubMed
Google Scholar
Lin HH, Zhang LL, Yan R, Lu JJ, Hu Y. Network analysis of drug-target interactions: a study on FDA-approved new molecular entities between 2000 to 2015. Sci Rep. 2017;7(1):12230.
PubMed
PubMed Central
Google Scholar
Feng YY, Ji HY, Dong XD, Liu AJ. An alcohol-soluble polysaccharide from Atractylodes macrocephala Koidz induces apoptosis of Eca-109 cells. Carbohydr Polym. 2019;226: 115136.
CAS
PubMed
Google Scholar
Ni H, Xu S, Gu P, Wusiman A, Zhang Y, Qiu T, et al. Optimization of preparation conditions for CTAB-modified Polygonatum sibiricum polysaccharide cubosomes using the response surface methodology and their effects on splenic lymphocytes. Int J Pharm. 2019;559:410–9.
CAS
PubMed
Google Scholar
Liu Z, Sun Y, Zhang J, Ou N, Gu P, Hu Y, et al. Immunopotentiation of Polysaccharides of Atractylodes macrocephala Koidz-loaded nanostructured lipid carriers as an adjuvant. Int J Biol Macromol. 2018;120:768–74.
CAS
PubMed
Google Scholar
Sun Y, Zhang J, Bo R, Ou N, Gu P, Liu Z, et al. Polysaccharides of Atractylodes macrocephala Koidz-loaded nanostructured lipid carriers: optimization on conditions by RSM and immunological activity in vitro. J Drug Deliv Sci Tec. 2018;44:305–13.
CAS
Google Scholar
Liu Z, Ni H, Yu L, Xu S, Bo R, Qiu T, et al. Adjuvant activities of CTAB-modified Polygonatum sibiricum polysaccharide cubosomes on immune responses to ovalbumin in mice. Int J Biol Macromol. 2020;148:793–801.
CAS
PubMed
Google Scholar
Zhang S, Pang G, Chen C, Qin J, Yu H, Liu Y, et al. Effective cancer immunotherapy by Ganoderma lucidum polysaccharide-gold nanocomposites through dendritic cell activation and memory T cell response. Carbohydr Polym. 2019;205:192–202.
CAS
PubMed
Google Scholar