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  1. The National Medical Products Administration (NMPA) in China has set to advance the regulatory capacity of traditional Chinese medicines (TCMs) with the adoption of regulatory science (RS). However, the priori...

    Authors: Zuanji Liang, Yunfeng Lai, Meng Li, Junnan Shi, Chi Ieong Lei, Hao Hu and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:23

    Content type: Review

    Published on:

  2. Galli gigeriae endothelium corneum (GGEC) has been effectively used for centuries for the treatment of functional dyspepsia (FD) in clinical practice in Asian countries. However, its potential mechanism and ch...

    Authors: Shanshan Li, Meng Zheng, Zhentang Zhang, Hengying Peng, Wenling Dai and Jihua Liu

    Citation: Chinese Medicine 2021 16:22

    Content type: Research

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  3. Both experimental and clinical studies have revealed satisfactory effects with the traditional Chinese formula Pinggan Qianyang decoction (PGQYD) for improving vascular remodeling caused by essential hypertens...

    Authors: Jiamei Yao, Cui Zhang, Yushu Yang, Xia Fang, Qiong Chen and Guangwei Zhong

    Citation: Chinese Medicine 2021 16:21

    Content type: Research

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  4. The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a compre...

    Authors: Hua Luo, Yi Zhao, Hua Hua, Yan Zhang, Xiaobo Zhang, Qingmao Fang, Qingmiao Li, Yiguan Zhang, Peng Tan, Andong Yang, Shunyuan Jiang, Lanping Guo, Cheng Peng, Yitao Wang, Luqi Huang and Junning Zhao

    Citation: Chinese Medicine 2021 16:19

    Content type: Review

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  5. Shende’an tablet (SDA) is a newly capsuled Chinese herbal formula derived from the Chinese traditional medicine Zhengan Xifeng Decoction which is approved for the treatment of neurasthenia and insomnia in Chin...

    Authors: Xiaoyan Sheng, Shuiyuan Yang, Xiaomin Wen, Xin Zhang, Yongfeng Ye, Peng Zhao, Limin Zang, Kang Peng, Enming Du and Sai Li

    Citation: Chinese Medicine 2021 16:18

    Content type: Research

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  6. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Meng–Huang Wu, Chuang–Yu Lin, Chun–Yin Hou, Ming–Thau Sheu and Hsi Chang

    Citation: Chinese Medicine 2021 16:17

    Content type: Correction

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    The original article was published in Chinese Medicine 2020 15:100

  7. Shikonin (SKO) is a natural naphthoquinone derived from Chinese herbal medicine Arnebiae Radix with high development potentials due to its anti-inflammatory and anti-tumor activities. Overwhelming evidences ha...

    Authors: Anqi Wang, Jiayu Liu, Yuhan Yang, Zhejie Chen, Caifang Gao, Zhanguo Wang, Chaomei Fu, Liang Zou and Shengpeng Wang

    Citation: Chinese Medicine 2021 16:16

    Content type: Research

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  8. Hereditary ataxia (HA) represents a group of genetically heterogeneous neurodegenerative diseases caused by dysfunction of the cerebellum or disruption of the connection between the cerebellum and other areas ...

    Authors: Michael Weng Lok Phang, Sze Yuen Lew, Ivy Chung, William Kiong-Seng Lim, Lee Wei Lim and Kah Hui Wong

    Citation: Chinese Medicine 2021 16:15

    Content type: Review

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  9. Suan-Zao-Ren Decoction (SZRD) has been widely used to treat neurological illnesses, including dementia, insomnia and depression. However, the mechanisms underlying SZRD’s improvement in cognitive function rema...

    Authors: Qing-Hua Long, Yong-Gui Wu, Li-Ling He, Li Ding, Ai-Hua Tan, He-Yuan Shi and Ping Wang

    Citation: Chinese Medicine 2021 16:14

    Content type: Research

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  10. Cholangiocarcinoma refers to an epithelial cell malignancy with poor prognosis. Yinchenhao decoction (YCHD) showed positive effects on cancers, and associations between YCHD and cholangiocarcinoma remain uncle...

    Authors: Zhiqiang Chen, Tong Lin, Xiaozhong Liao, Zeyun Li, Ruiting Lin, Xiangjun Qi, Guoming Chen, Lingling Sun and Lizhu Lin

    Citation: Chinese Medicine 2021 16:13

    Content type: Research

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  11. Panax notoginseng triol saponins (PTS) has been used clinically for ischemic stroke therapy (IST) in China for more than 17 years due to its anti-platelet aggregation and neuro-protective effects, but its mech...

    Authors: Zhi-yi Xu, Yang Xu, Xiao-fang Xie, Yin Tian, Jun-hui Sui, Yong Sun, Da-sheng Lin, Xing Gao, Cheng Peng and Yu-jiang Fan

    Citation: Chinese Medicine 2021 16:12

    Content type: Research

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  12. Despite the increased morbidity of ulcerative colitis (UC) in the developing countries, available treatments remain unsatisfactory. Therefore, it is urgent to discover more effective therapeutic strategies. Pulsa...

    Authors: Yong Zhang, Zhengxia Zha, Wenhua Shen, Dan Li, Naixin Kang, Zhong Chen, Yanli Liu, Guoqiang Xu and Qiongming Xu

    Citation: Chinese Medicine 2021 16:11

    Content type: Research

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  13. Electroacupuncture (EA) is generally accepted as a safe and harmless treatment option for alleviating depression. However, there are several challenges related to the use of EA. Although EA has been shown to b...

    Authors: Xuke Han, Yang Gao, Xuan Yin, Zhangjin Zhang, Lixing Lao, Qiu Chen and Shifen Xu

    Citation: Chinese Medicine 2021 16:10

    Content type: Review

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    The Correction to this article has been published in Chinese Medicine 2021 16:20

  14. Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that may progress into, in the absence of proper treatment, severe liver damage. While the optimal pharmacotherapy for NAFLD remains uncertai...

    Authors: Zuanji Liang, Xianwen Chen, Junnan Shi, Hao Hu, Yan Xue and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:9

    Content type: Review

    Published on:

  15. Fingerprint analysis and simultaneous multi-components determination are crucial for the holistic quality control of traditional Chinese medicines (TCMs). Yet, reference standards (RS) are often commercially u...

    Authors: Qingjun Wang, Xinlan Yu, Lei Sun, Runtao Tian, Huaizhen He, Sicen Wang and Shuangcheng Ma

    Citation: Chinese Medicine 2021 16:8

    Content type: Research

    Published on:

  16. Increasing evidence have indicated the relationship between intestinal dysbiosis and hypertension. We aimed to evaluate the effect of the electroacupuncture (EA) on intestinal microbiota in patients with stage...

    Authors: Jun-meng Wang, Ming-xiao Yang, Qiao-feng Wu, Ji Chen, Shu-fang Deng, Lin Chen, Da-neng Wei and Fan-rong Liang

    Citation: Chinese Medicine 2021 16:7

    Content type: Research

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  17. Patchouli (“Guanghuoxiang”) or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In ...

    Authors: Chen Junren, Xie Xiaofang, Li Mengting, Xiong Qiuyun, Li Gangmin, Zhang Huiqiong, Chen Guanru, Xu Xin, Yin Yanpeng, Peng Fu and Peng Cheng

    Citation: Chinese Medicine 2021 16:5

    Content type: Review

    Published on:

  18. To investigate the microRNA (miRNA)-gene interactions underlying leukocyte functions and characteristics, especially the potential serum biomarkers, implicated in the traditional Chinese medicine (TCM)-defined...

    Authors: Leiming You, Shen Zhang, Ting’an Li, Xiaopu Sang, Kunyu Li, Wei Wang, Xinhui Gao, Jiarui Wu, Guangrui Huang, Ting Wang and Anlong Xu

    Citation: Chinese Medicine 2021 16:4

    Content type: Research

    Published on:

  19. OPD and OPD' are the two main active components of Ophiopogon japonicas in Shenmai injection (SMI). Being isomers of each other, they are supposed to have similar pharmacological activities, but the actual sit...

    Authors: Huan-Hua Xu, Zhen-Hong Jiang, Cong-Shu Huang, Yu-Ting Sun, Long-Long Xu, Xiang-Ling Tang, Hong-Ling Tan, Zeng-Chun Ma and Yue Gao

    Citation: Chinese Medicine 2021 16:3

    Content type: Research

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  20. Insomnia as one of the dominant diseases of traditional Chinese medicine (TCM) has been extensively studied in recent years. To explore the novel approaches of research on TCM diagnosis and treatment, this pap...

    Authors: Yuqi Tang, Zechen Li, Dongdong Yang, Yu Fang, Shanshan Gao, Shan Liang and Tao Liu

    Citation: Chinese Medicine 2021 16:2

    Content type: Research

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  21. The onset of neurodegenerative disease has not only been a major cause of scientific worry, but of economic burden to the health system. This condition has been further attributed to mis-stability, deletion or...

    Authors: Abdullahi Alausa, Sunday Ogundepo, Barakat Olaleke, Rofiat Adeyemi, Mercy Olatinwo and Aminat Ismail

    Citation: Chinese Medicine 2021 16:1

    Content type: Review

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  22. Infections induced by influenza viruses, as well as coronavirus disease 19 (COVID-19) pandemic induced by severe acute respiratory coronavirus 2 (SARS-CoV-2) led to acute lung injury (ALI) and multi organ fail...

    Authors: Peng Tu, Rong Tian, Yan Lu, Yunyi Zhang, Haiyan Zhu, Lijun Ling, Hong Li and Daofeng Chen

    Citation: Chinese Medicine 2020 15:128

    Content type: Research

    Published on:

  23. Indigo naturalis is a blue dye in ancient, as well as an extensive used traditional Chinese medicine. It has a wide spectrum of pharmacological properties and can be used to treat numerous ailments such as leu...

    Authors: Yang Qi-yue, Zhang Ting, He Ya-nan, Huang Sheng-jie, Deng Xuan, Han Li and Xie Chun-guang

    Citation: Chinese Medicine 2020 15:127

    Content type: Review

    Published on:

  24. Autophagy is a highly conserved degradation process for long-lived intracellular proteins and organelles mediated by lysosomes. Deficits in the autophagy-lysosome pathway (ALP) have been linked to a variety of...

    Authors: Jie Xu, Xiao-Qi Zhang and Zaijun Zhang

    Citation: Chinese Medicine 2020 15:123

    Content type: Review

    Published on:

  25. Liver ischemia/reperfusion (I/R) injury is an inevitable pathological phenomenon in various clinical conditions, such as liver transplantation, resection surgery, or shock, which is the major cause of morbidit...

    Authors: Zheng Wang, Ping Zhang, Qingqing Wang, Xueping Sheng, Jianbing Zhang, Xiaoyan Lu and Xiaohui Fan

    Citation: Chinese Medicine 2020 15:122

    Content type: Research

    Published on:

  26. Diabetes is a complex metabolic disease characterized by hyperglycemia, plaguing the whole world. However, the action mode of multi-component and multi-target for traditional Chinese medicine (TCM) could be a ...

    Authors: Yunfei Song, Jianbo Yang, Wenguang Jing, Qi Wang, Yue Liu, Xianlong Cheng, Fei Ye, Jinying Tian, Feng Wei and Shuangcheng Ma

    Citation: Chinese Medicine 2020 15:121

    Content type: Research

    Published on:

  27. This study was aimed to investigate the therapeutic effects and potential mechanism of higenamine combined with [6]-gingerol (HG/[6]-GR) against doxorubicin (DOX)—induced chronic heart failure (CHF) in rats.

    Authors: Jianxia Wen, Xiao Ma, Ming Niu, Junjie Hao, Ying Huang, Ruilin Wang, Ruisheng Li, Jian Wang and Yanling Zhao

    Citation: Chinese Medicine 2020 15:120

    Content type: Research

    Published on:

  28. Naoshuantong capsule (NSTC) is an oral Chinese medicine formula composed of Typhae Pollen, Radix Paeoniae Rubra, Curcumae Radix, Gastrodiae Rhizoma and Radix Rhapontici. It has been widely used at the acute an...

    Authors: Lvkeng Luo, Shuling Wu, Ruiqi Chen, Hongyu Rao, Wei Peng and Weiwei Su

    Citation: Chinese Medicine 2020 15:119

    Content type: Research

    Published on:

  29. Cancer cells through autophagy-mediated recycling to meet the metabolic demands of growth and proliferation. The steroidal saponin 20(S)-ginsenoside Rh2 effectively inhibits the growth and survival of a variet...

    Authors: Jiawen Wang, Shuai Bian, Siming Wang, Song Yang, Wanying Zhang, Daqing Zhao, Meichen Liu and Xueyuan Bai

    Citation: Chinese Medicine 2020 15:118

    Content type: Research

    Published on:

  30. The use of anti-inflammatory and analgesic drugs such as nonsteroidal anti-inflammatory drugs(NSAIDs) for treating acute gout has limitations, such as adverse reactions in the gastrointestinal tract and toxici...

    Authors: Shuang Ren, Fanyan Meng, Yantong Liu, Yun Meng, Ning Tao, Ruoshi Liu and Jie Zhang

    Citation: Chinese Medicine 2020 15:117

    Content type: Research

    Published on:

  31. Stroke in Chinese Medicine (CM) includes the concepts of ischemic and hemorrhagic strokes from Western Medicine and is a common disease in Hong Kong. This clinical practice guideline (CPG) aims to evaluate and...

    Authors: Linda L. D. Zhong, Wai Kun, Nannan Shi, Tat Chi Ziea, Bacon F. L. Ng, Ying Gao, Zhaoxiang Bian and Aiping Lu

    Citation: Chinese Medicine 2020 15:116

    Content type: Commentary

    Published on:

  32. The outbreak of COVID-19 has recently evolved into a global pandemic. Up to July 2020, almost every country has confirmed COVID-19 cases reported worldwide. Many leading experts have predicted that the epidemi...

    Authors: Hua Luo, Mingming Zhao, Dechao Tan, Chang Liu, Lin Yang, Ling Qiu, Yan Gao and Hua Yu

    Citation: Chinese Medicine 2020 15:115

    Content type: Review

    Published on:

  33. Spleen-deficiency syndrome, an important pathological change in traditional Chinese medicine, has been proven to attribute to intestinal dysbacteriosis. Shengmai Yin (SMY), a classic formula for replenishing q...

    Authors: Yu You, Lin Luo, Yanyan You, Yanjun Lin, Huiling Hu, Yunhui Chen, Chaomei Fu and Tian Xie

    Citation: Chinese Medicine 2020 15:114

    Content type: Research

    Published on:

  34. Yuzhi Zhixue Granule (YZG) is a traditional Chinese patent medicine for treating excessive menstrual flow caused by ovulatory dysfunctional uterine bleeding (ODUB) accompanied by heat syndrome. However, the un...

    Authors: Jialin Li, Hua Luo, Xinkui Liu, Jingyuan Zhang, Wei Zhou, Siyu Guo, Xiuping Chen, Yingying Liu, Shanshan Jia, Haojia Wang, Bingbing Li, Guoliang Cheng and Jiarui Wu

    Citation: Chinese Medicine 2020 15:113

    Content type: Research

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  35. BaelanChagsangBang (BCB), a herbal formulation consisting of eleven herbs, may be prescribed as a reproductive functional supplement to improve ovulation and implantation during the treatment of infertility an...

    Authors: Songhee Jeon, Quan Feng Liu, Hua Cai, Ha Jin Jeong, Su-Hyun Kim, Dong-Il Kim and Ju-Hee Lee

    Citation: Chinese Medicine 2020 15:112

    Content type: Research

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  36. Ganoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture.

    Authors: Mei-Ting Liu, Ling-Xiao Chen, Jing Zhao and Shao-Ping Li

    Citation: Chinese Medicine 2020 15:111

    Content type: Research

    Published on:

  37. Trilobatin, a natural compound, has been found to exhibit anti-diabetic properties in high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic mice. But up to now no research has been reported on t...

    Authors: Min Liu, Lujing Wang, Xigan Li, Yucui Wu, Fei Yin and Jianhui Liu

    Citation: Chinese Medicine 2020 15:110

    Content type: Research

    Published on:

  38. Allergic rhinitis (AR) is a common symptomatic, inflammatory, and immunological disorder of nasal mucosa. Multiple clinical trials and systematic reviews have implicated acupuncture methods as potentially effe...

    Authors: Zihan Yin, Guoyan Geng, Guixing Xu, Ling Zhao and Fanrong Liang

    Citation: Chinese Medicine 2020 15:109

    Content type: Review

    Published on:

  39. Around 15% of the Hong Kong population was found to suffer from overactive bladder (OAB), but the current available treatments, such as medication, behavioral therapy and physical therapy are unsatisfactory. P...

    Authors: Zhi-xiu Lin, Ngai Ho Tony Chan, Yiu-keung Kwan, Yu Tat Chan, Hongwei Zhang, Kam-yuk Sylvia Tam, Mei Kwan Lai, Chun-Kam Lee, Kit Ngan, Stella Yin Yuen Tsoi, Yiu Wa Lau, Yan-Fang Xian, Jessica Ching and Yuanqi Guo

    Citation: Chinese Medicine 2020 15:108

    Content type: Research

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  40. Ophiocordyceps sinensis, which is only naturally found in the high-elevation extreme environment of the Tibetan Plateau, has been used in traditional Chinese medicine. Information concerning the evolutionary and ...

    Authors: Jie Liu, Linong Guo, Zongwei Li, Zhe Zhou, Zhen Li, Qian Li, Xiaochen Bo, Shengqi Wang, Junli Wang, Shuangcheng Ma, Jian Zheng and Ying Yang

    Citation: Chinese Medicine 2020 15:107

    Content type: Research

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  41. Neuropathic pain is a debilitating pathological pain condition with a great therapeutic challenge in clinical practice. Currently used analgesics produce deleterious side effects. Therefore, it is necessary to...

    Authors: Chunhao Zhu, Ning Liu, Miaomiao Tian, Lin Ma, Jiamei Yang, Xiaobing Lan, Hanxiang Ma, Jianguo Niu and Jianqiang Yu

    Citation: Chinese Medicine 2020 15:106

    Content type: Review

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  42. Migraine is painful disease in which neurotransmitters related to pain transmission play an important role. Hejie Zhitong prescription (HJZT) has been used in the clinic as an effective prescription for the tr...

    Authors: Xinna Wang, Hongfei Zhao, Liming Liu, Ping Niu, Chao Zhai, Jinjian Li, Qiaoli Xu and Dexi Zhao

    Citation: Chinese Medicine 2020 15:105

    Content type: Research

    Published on:

  43. Moxibustion is one of the major interventions of Chinese medicine (CM). The systematic reviews (SRs) are essential references for evaluating the efficacy and safety of moxibustion interventions. This study aim...

    Authors: Ran Tian, Xuan Zhang, Si-Yao Li, Qi-Ying Aixinjueluo, Wai Ching Lam and Zhao-Xiang Bian

    Citation: Chinese Medicine 2020 15:104

    Content type: Research

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  44. The dry body of the Tokay Gecko (Gekko gecko) is the source of a valuable traditional Chinese medicine, it is therefore listed as a Class II protected animal species in China. Due to increasing market demand and ...

    Authors: Yanyan Su, Dandan Ding, Mengjie Yao, Lan Wu, Gangqiang Dong, Dong Zhang, Shilin Chen and Li Xiang

    Citation: Chinese Medicine 2020 15:103

    Content type: Research

    Published on: