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  1. Several natural products have been demonstrated to be effective in the treatment of depressive disorders. Echinacoside, a naturally occurring phenol extracted from Cistanche tubulosa, Echinacea angustifolia, and

    Authors: Han-Wen Chuang, Tse-Yen Wang, Chih-Chia Huang and I-Hua Wei
    Citation: Chinese Medicine 2022 17:9
  2. This study aims to develop an evidence-based clinical practice guideline of acupuncture in the treatment of patients with moderate and severe cancer pain.

    Authors: Long Ge, Qi Wang, Yihan He, Darong Wu, Qi Zhou, Nenggui Xu, Kehu Yang, Yaolong Chen, Anthony Lin Zhang, Haiqing Hua, Jinchang Huang, Ka-Kit Hui, Fanrong Liang, Linpeng Wang, Bin Xu, Yufei Yang…
    Citation: Chinese Medicine 2022 17:8
  3. Stimulator of IFN genes (STING) is highly expressed in the livers of non-alcoholic fatty liver disease (NAFLD) patients and high fat diet (HFD) induced NAFLD mice model. The STING signaling-mediated inflammati...

    Authors: Lin Cao, Erjin Xu, Rendong Zheng, Zhili Zhangchen, Rongling Zhong, Fei Huang, Juan Ye, Hongping Sun, Yaofu Fan, Shaofeng Xie, Yu Chen, Yijiao Xu, Jing Cao, Wen Cao and Chao Liu
    Citation: Chinese Medicine 2022 17:7
  4. Dizziness and vertigo are common clinical symptoms. Gastrodin injection has shown clinical effects on dizziness or vertigo. However, little is known about the effectiveness and costs of combining Gastrodin inj...

    Authors: Yunfeng Lai, Ruoning Wang, Wei Li, He Zhu, Shuyang Fei, Honghao Shi, Nan Lu, Carolina Oi Lam Ung, Hao Hu and Sheng Han
    Citation: Chinese Medicine 2022 17:6
  5. China has introduced a series of polices and practice to manage the market access of Chinese patent medicine (CPM) products into its healthcare security system, which is less analyzed and reported in current l...

    Authors: Chenglai Xia, Dongning Yao, Yunfeng Lai, Yan Xue and Hao Hu
    Citation: Chinese Medicine 2022 17:5
  6. We investigate the chemical basis and mechanism of angiogenesis regulation by a multicomponent Chinese medicine Danhong injection (DHI).

    Authors: Shuang He, Rongrong Chen, Li Peng, Zhenzuo Jiang, Haixin Liu, Zihao Chen, Tiechan Zhao, John Owoicho Orgah, Jie Ren, Peng Zhang, Yuefei Wang, Xiumei Gao and Yan Zhu
    Citation: Chinese Medicine 2022 17:4
  7. Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied with itchy and scaly rash. Compound traditional Chinese medicine dermatitis ointment (CTCMDO) consists of a mixture of extracts from fi...

    Authors: Rongrong Zhang, Hongyin Zhang, Shuai Shao, Yingxin Shen, Fengqin Xiao, Jiaming Sun, Songlan Piao, Daqing Zhao, Guangzhe Li and Mingming Yan
    Citation: Chinese Medicine 2022 17:3
  8. Growing clinical evidences show the potentials of Colquhounia root tablet (CRT) in alleviating diabetic kidney disease (DKD). However, its pharmacological properties and underlying mechanisms remain unclear.

    Authors: Zhaochen Ma, Yudong Liu, Congchong Li, Yanqiong Zhang and Na Lin
    Citation: Chinese Medicine 2022 17:2
  9. Qingwei San (QWS), one of classic Chinese Medicine prescripts, has been widely used to treat stomach heat syndrome which manifests oral ulcer (OU), periodontitis and upper gastrointestinal bleeding for seven h...

    Authors: Lu Shi, Yongcheng An, Long Cheng, Yiyang Li, Huimin Li, Chen Wang, Yinglan Lv, Yuhui Duan, Hongyu Dai, Changhao He, Huilin Zhang, Yan Huang, Wanxin Fu, ShengPeng Wang, Baosheng Zhao, Yitao Wang…
    Citation: Chinese Medicine 2022 17:1
  10. Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own h...

    Authors: Yan Liu, Xiaojie Li, Cai Chen, Aijing Leng and Jialin Qu
    Citation: Chinese Medicine 2021 16:143

    The Correction to this article has been published in Chinese Medicine 2022 17:10

  11. Liver fibrosis develops from various chronic liver diseases, and there is currently a lack of specific treatment strategies. Yiqi Rougan decoction (YQRG) is a traditional Chinese medicine that has shown durati...

    Authors: Yu Xiong, Jinyuan Hu, Chen Xuan, Jiayu Tian, Kaiyue Tan, Zhiwei Chen, Yan Luo, Xuqin Du, Junxiong Cheng, Lanyue Zhang and Wenfu Cao
    Citation: Chinese Medicine 2021 16:142
  12. The decrease of wild reserves and the sharp increase of market demand have led to resource substitution, but it is still not clear how to discover medicinal alternative resources. Here we reveal the biology of...

    Authors: Ning Cui, Tiezhu Chen, Baosheng Liao, Jiang Xu and Xiwen Li
    Citation: Chinese Medicine 2021 16:141
  13. Prokinetic is the first-line conventional treatment for functional dyspepsia (FD) in Asia despite potential adverse events. Chinese herbal medicine (CHM) may be an effective and safe substitution. This network...

    Authors: Leonard Ho, Claire C. W. Zhong, Charlene H. L. Wong, Justin C. Y. Wu, Karina K. H. Chan, Irene X. Y. Wu, Ting Hung Leung and Vincent C. H. Chung
    Citation: Chinese Medicine 2021 16:140
  14. The P2Y12 receptor is a kind of purinoceptor that is engaged in platelet aggregation, and P2Y12 inhibitors have been used in clinical antithrombotic therapy. The P2Y12 receptor in microglia induces interleukin...

    Authors: Yanzhen Li, Hong Zhang, Jingwen Yang, Muouyang Zhan, Xuefei Hu, Yongmin Liu, Lingling Yu, Xiaochen Yan, Shangdong Liang, Ruyue Zhang, Ying Lu, Beining Li, Cunzhi Liu and Man Li
    Citation: Chinese Medicine 2021 16:139
  15. Chinese medicine (CM) has a long history in the treatment of psoriasis, and its different understanding angle and treatment mode from modern medicine have unique wisdom. In this article, we consulted a large n...

    Authors: Yang Su, Wen Qin, Lun Wu, Bingyou Yang, Qiuhong Wang, Haixue Kuang and Genhong Cheng
    Citation: Chinese Medicine 2021 16:138
  16. Acupuncture has shown beneficial effects for seasonal allergic rhinitis (SAR); however, it is time and cost intensive. We investigated feasibility and effects of self-administered body acupressure as a self-ca...

    Authors: Lukas Israel, Gabriele Rotter, Ulrike Förster-Ruhrmann, Josef Hummelsberger, Rainer Nögel, Andreas Michalsen, Tatjana Tissen-Diabaté, Sylvia Binting, Thomas Reinhold, Miriam Ortiz and Benno Brinkhaus
    Citation: Chinese Medicine 2021 16:137
  17. Vascular cognitive dysfunction in patients with vascular dementia (VD) is a kind of severe cognitive dysfunction syndrome caused by cerebrovascular diseases. At present, effective drugs to improve the cognitiv...

    Authors: Yue Qiu, Xian-jun Xue, Geng Liu, Miao-miao Shen, Chun-yan Chao, Jie Zhang, Ya-qi Guo, Qian-qian Niu, Ya-nan Yu, Yu-ting Song, Huan-huan Wang, Shuang-xi Wang, Yu-jing Chen, Lin-hua Jiang, Peng Li and Ya-ling Yin
    Citation: Chinese Medicine 2021 16:136
  18. Drug-induced liver injury (DILI) is a common adverse drug reaction (ADR) and a serious threat to health that affects disease treatments. At present, no targeted clinical drugs are available for DILI. Tradition...

    Authors: Yongfeng Zhou, Junnan Wang, Dingkun Zhang, Jiaxin Liu, Qinghua Wu, Jiang Chen, Peng Tan, Boyu Xing, Yanzhong Han, Ping Zhang, Xiaohe Xiao and Jin Pei
    Citation: Chinese Medicine 2021 16:135
  19. Our previous studies have shown that evodiamine (EVO) as paclitaxel and nocodazole could trigger apoptosis in various human cancer cells including human renal cell carcinoma cells, colorectal carcinoma cells, ...

    Authors: Chih-Chiang Chien, Ming-Shun Wu, Shih-Wei Chou, Ganbolor Jargalsaikhan and Yen-Chou Chen
    Citation: Chinese Medicine 2021 16:134
  20. Colorectal cancer (CRC) is one of the common gastrointestinal malignancies, tumor heterogeneity is the main cause of refractory CRC. Syndrome differentiation is the premise of individualized treatment of tradi...

    Authors: Yiyu Lu, Chungen Zhou, Meidong Zhu, Zhiliang Fu, Yong Shi, Min Li, Wenhai Wang, Shibo Zhu, Bin Jiang, Yunquan Luo and Shibing Su
    Citation: Chinese Medicine 2021 16:133
  21. Depression is a severe neuropsychiatric disorder that affects more than 264 million people worldwide. The efficacy of conventional antidepressants are barely adequate and many have side effects. Hericium erinaceu...

    Authors: Pit Shan Chong, Chi Him Poon, Jaydeep Roy, Ka Chun Tsui, Sze Yuen Lew, Michael Weng Lok Phang, Rachael Julia Yuenyinn Tan, Poh Guat Cheng, Man-Lung Fung, Kah Hui Wong and Lee Wei Lim
    Citation: Chinese Medicine 2021 16:132
  22. The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clin...

    Authors: Mu-Feng Xiang, Cheng-Tao Jin, Li-Hua Sun, Zhi-Hui Zhang, Jing-Jing Yao and Liu-Cheng Li
    Citation: Chinese Medicine 2021 16:130
  23. The high incidence of breast cancer is the greastest threat to women’ health all over the world. Among them, HER-2 positive breast cancer has the characteristics of high malignancy, easy recurrence and metasta...

    Authors: Huajuan Jiang, Minmin Li, Kequn Du, Chuan Ma, Yanfen Cheng, Shengju Wang, Xin Nie, Chaomei Fu and Yao He
    Citation: Chinese Medicine 2021 16:129
  24. Shen-Zhi-Ling oral liquid (SZL) is an herbal formula known for its efficacy of nourishing “heart and spleen”, and is used for the treatment and prevention of middle- and early-stage dementia. This study invest...

    Authors: Gaofeng Qin, Yunfang Dong, Zhenhong Liu, Zhuoyan Gong, Chenyan Gao, Mingcui Zheng, Meijing Tian, Yannan He, Liqun Zhong and Pengwen Wang
    Citation: Chinese Medicine 2021 16:128

    The Correction to this article has been published in Chinese Medicine 2021 16:144

  25. Honokiol (HKL) has been reported to ameliorate lipopolysaccharide (LPS)-induced acute lung injury (ALI). However, its potential mechanism of its protective effects remains unclear. In this study, the protectiv...

    Authors: Yuhan Liu, Jiabin Zhou, Yingying Luo, Jinxiao Li, Luorui Shang, Fangyuan Zhou and Shenglan Yang
    Citation: Chinese Medicine 2021 16:127
  26. Lung cancer remains the leading cause of mortality from malignant tumors, non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases, and individualized diagnosis and treatment is an eff...

    Authors: Song Cang, Ran Liu, Wei Jin, Qi Tang, Wanjun Li, Kunqian Mu, Pengfei Jin, Kaishun Bi and Qing Li
    Citation: Chinese Medicine 2021 16:126
  27. In South-east Asia, Dipterocarpoideae is predominant in most mature forest communities, comprising around 20% of all trees. As large quantity and high quality wood are produced in many species, Dipterocarpoide...

    Authors: Yang Yu, Yuwei Han, Yingmei Peng, Zunzhe Tian, Peng Zeng, Hang Zong, Tinggan Zhou and Jing Cai
    Citation: Chinese Medicine 2021 16:125
  28. Osteosarcoma is a malignant tumor of bone and soft tissue in adolescents. Due to its tumor biological behavior pattern, osteosarcoma usually generates poor prognosis. Autophagy is an important self-defense mec...

    Authors: Jiaming He, Wenkan Zhang, Xiaozhong Zhou, Weiqi Yan and Zhan Wang
    Citation: Chinese Medicine 2021 16:123
  29. Codonopsis pilosula, an important medicinal plant, can accumulate certain metabolites under moderate drought stress. Endophytes are involved in the metabolite accumulations within medicinal plants. It is still un...

    Authors: Yichuan Liang, Guangfei Wei, Kang Ning, Guozhuang Zhang, Youping Liu, Linlin Dong and Shilin Chen
    Citation: Chinese Medicine 2021 16:122
  30. Compound kushen injection (CKI), a Chinese patent drug, is widely used in the treatment of various cancers, especially neoplasms of the digestive system. However, the underlying mechanism of CKI in pancreatic ...

    Authors: Chao Wu, Zhi-Hong Huang, Zi-Qi Meng, Xiao-Tian Fan, Shan Lu, Ying-Ying Tan, Lei-Ming You, Jia-Qi Huang, Antony Stalin, Pei-Zhi Ye, Zhi-Shan Wu, Jing-Yuan Zhang, Xin-Kui Liu, Wei Zhou, Xiao-Meng Zhang and Jia-Rui Wu
    Citation: Chinese Medicine 2021 16:121
  31. Weifuchun (WFC), a Chinese herbal prescription consisting of Red Ginseng, Isodon amethystoides and Fructus Aurantii, is commonly used in China to treat a variety of chronic stomach disorders. The aim of the pa...

    Authors: Yanqin Bian, Xi Chen, Hongyan Cao, Dong Xie, Meiping Zhu, Nong Yuan, Lu Lu, Bingjie Lu, Chao Wu, Nisma Lena Bahaji Azami, Zheng Wang, Huijun Wang, Yeqing Zhang, Kun Li, Guan Ye and Mingyu Sun
    Citation: Chinese Medicine 2021 16:120
  32. Cardiomyopathy is a kind of cardiovascular diseases, which makes it more difficult for the heart to pump blood to other parts of the body, eventually leading to heart failure. Naoxintong (NXT), as a traditiona...

    Authors: Mengyan Hu, Peirong Liu, Shuxian Lu, Zhihao Wang, Zhaojie Lyu, Hongkai Liu, Yuhong Sun, Feng Liu and Jing Tian
    Citation: Chinese Medicine 2021 16:119
  33. Buyang Huanwu Decoction (BHD) is a classical Chinese Medicine formula empirically used for diabetic nephropathy (DN). However, its therapeutic efficacies and the underlying mechanisms remain obscure. In our st...

    Authors: Weifeng Wu, Yifan Wang, Haidi Li, Haiyong Chen and Jiangang Shen
    Citation: Chinese Medicine 2021 16:118
  34. Irritable bowel syndrome (IBS) is a common gastrointestinal functional disease. Adults with IBS may experience abdominal pain, change of bowel habits, and abnormal stool form without organic disease. IBS can s...

    Authors: Ya Zheng, Jessica Ching, Chung Wah Cheng, Wai Ching Lam, Kam Leung Chan, Xuan Zhang, Pui Yan Lam, Xing Yao Wu, Linda L. D. Zhong, Pei Hua Cao, Cho Wing Lo, Pui Kuan Cheong, Zhixiu Lin, Matthew Koh, Justin Wu and Zhao Xiang Bian
    Citation: Chinese Medicine 2021 16:117
  35. Arsenic (As3+) is a carcinogen with considerable environmental and occupational relevancy. Its mechanism of action and methods of prevention remain to be investigated. Previous studies have demonstrated that ROS ...

    Authors: Yuan-Ye Dang, Hua Luo, Yong-Mei Li, Yang Zhou, Xiu Luo, Shui-Mu Lin, Shou-Ping Liu, Simon Ming-Yuen Lee, Chu-Wen Li and Xiao-Yan Dai
    Citation: Chinese Medicine 2021 16:116
  36. Non-alcoholic fatty liver disease (NAFLD) is characterized by ectopic accumulation of triglycerides in the liver. Emerging evidence has demonstrated that lipophagy regulates lipid mobilization and energy homeo...

    Authors: Jingxin Liu, Tian Zhang, Jianzhong Zhu, Shuangchen Ruan, Rongsong Li, Bing Guo and Ligen Lin
    Citation: Chinese Medicine 2021 16:115
  37. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease dominated by synovial hyperplasia and bone destruction. The male flower of Eucommia ulmoides Oliv. (EF) has been shown to exert effects on the in...

    Authors: Yan Zhang, Jian-Ying Wang, Hao Wang, Xiao-Yun Chen, Lei Zhang and Ying Yuan
    Citation: Chinese Medicine 2021 16:113
  38. Fibrotic liver injury is a progressive scarring event, which may permanently affect liver function and progress into devastating end-stage liver diseases due to the absence of effective therapies. Si-Wu-Tang (...

    Authors: Xiaoyong Xue, Jianzhi Wu, Mingning Ding, Feng Gao, Fei Zhou, Bing Xu, Mingjun Lu, Jun Li and Xiaojiaoyang Li
    Citation: Chinese Medicine 2021 16:112
  39. Common chronic wounds include diabetic ulcers, venous ulcers, and pressure ulcers. The traditional Chinese medicine Huiyang Shengji decoction (HYSJD) has been shown to promote the healing of diabetic chronic w...

    Authors: Qingwu Liu, Jinchao Zhang, Xuyang Han, Jia Chen, Yating Zhai, Yan Lin, Huike Ma, Fang Feng, Xiujuan He and Ping Li
    Citation: Chinese Medicine 2021 16:111
  40. Uncaria tomentosa, which has similar chemical constituents with Uncaria rhynchophylla, has been reported to alleviate cognitive impairments in Alzheimer’s disease (AD) animal models. This study aimed to compare t...

    Authors: Qing-Qing Xu, Pang Chui Shaw, Zhen Hu, Wen Yang, Siu-Po Ip, Yan-Fang Xian and Zhi-Xiu Lin
    Citation: Chinese Medicine 2021 16:110
  41. Traditional Chinese Medicine (TCM) is distinguished by Syndrome differentiation, which prescribes various formulae for different Syndromes of same disease. This study aims to investigate the underlying mechanism.

    Authors: Gaosong Wu, Jing Zhao, Jing Zhao, Nixue Song, Ningning Zheng, Yuanyuan Zeng, Tingting Yao, Jingfang Zhang, Jieqiong Weng, Mengfei Yuan, Hu Zhou, Xiaoxu Shen, Houkai Li and Weidong Zhang
    Citation: Chinese Medicine 2021 16:109
  42. Coronary heart disease (CHD) is a common ischaemic heart disease whose pathological mechanism has not been fully elucidated. Single target drugs, such as antiplatelet aggregation, coronary artery dilation and ...

    Authors: Tian-Yi Cheng, Jia-Xin Li, Jing-Yi Chen, Pei-Ying Chen, Lin-Rui Ma, Gui-Lin Zhang and Pei-Yu Yan
    Citation: Chinese Medicine 2021 16:108
  43. Lily Bulb and Rehmannia Decoction (LBRD), is a traditional Chinese formula that has been shown to be safe and effective against depression; however, its material basis and pharmacological mechanisms remain unk...

    Authors: Hongxiu Zhang, Xiaoyan Xue, Jin Pan, Xiaobin Song, Xing Chang, Qiancheng Mao, Yanting Lu, Haijun Zhao, Yuan Wang, Xiansu Chi, Shijun Wang and Ke Ma
    Citation: Chinese Medicine 2021 16:107
  44. The wide spread of plasmid-mediated colistin resistance by mobile colistin resistance (MCR) in Enterobacteriaceae severely limits the clinical application of colistin as a last-line drug against bacterial infe...

    Authors: Qiushuang Sheng, Runbao Du, Cunhui Ma, Yonglin Zhou, Xue Shen, Xiaoning Hou, Lei Xu, Li Li, Xuming Deng and Jianfeng Wang
    Citation: Chinese Medicine 2021 16:106
  45. Neonatal hypoxic-ischemic encephalopathy (HIE) refers to the perinatal asphyxia caused by the cerebral hypoxic-ischemic injury. The current study was aimed at investigating the therapeutic efficacy of Scutella...

    Authors: Rui-Ze Niu, Liu-Lin Xiong, Hao-Li Zhou, Lu-Lu Xue, Qing-Jie Xia, Zheng Ma, Yuan Jin, Li Chen, Ya Jiang, Ting-Hua Wang and Jia Liu
    Citation: Chinese Medicine 2021 16:105